CAS 615-58-7

2,4-dibromophenol

Codes：FEBU-023

Application context (from source-drug indications)

高尿酸血症非布司他痛风非布司他颅内出血非布司他溃疡性结肠炎非布司他慢性肾功能不全非布司他疼痛非布司他

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
非布司他Febuxostat	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

非布司他优化路线steps: 5total yield: 1.29 g

ethyl 2-chloro-3-oxobutanoate→1-bromo-2-methylpropane→ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate→2,4-dibromophenol→2,4-dibromo-1-isobutoxybenzene→4-isobutoxyisophthalonitrile→3-cyano-4-isobutoxybenzothioamide

Intermediates available on this site

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Supplier	Product	Price band	MOQ	Lead time	Qualifications
Qualified Partner — East China API Works	Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate Pharmaceutical Intermediates	询价	询价	询价	—
Unibest Nantong cGMP Site	Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate Pharmaceutical Intermediates	询价	询价	询价	—

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