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CAS 70381-75-8
ethyl 2-(5,6-dichloro-2-imino-1,2-dihydroquinazolin-3(4H)-yl)acetate hydrobromide
Codes: ANAG-023
Application context (from source-drug indications)
Essential thrombocythaemiaAnagrelide Hydrochloride HydrateMyeloproliferative neoplasmAnagrelide Hydrochloride Hydrate血小板增多Anagrelide Hydrochloride HydrateMyelofibrosisAnagrelide Hydrochloride HydrateChronic myeloid leukaemiaAnagrelide Hydrochloride HydratePolycythaemia veraAnagrelide Hydrochloride Hydrate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Anagrelide Hydrochloride Hydrate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
ethyl 2-((6-amino-2,3-dichlorobenzyl)amino)acetate→3-chloroaniline→2,2,2-trichloroethane-1,1-diol→(E)-N-(3-chlorophenyl)-3-hydroxyacrylamide→4-chloroindoline-2,3-dione→4,5-dichloroindoline-2,3-dione→6-amino-2,3-dichlorobenzoic acid→(6-amino-2,3-dichlorophenyl)methanol→3,4-dichloro-2-(chloromethyl)aniline hydrochloride→aminomethyl propionate hydrochloride→ethyl 2-(5,6-dichloro-2-imino-1,2-dihydroquinazolin-3(4H)-yl)acetate hydrobromide→6,7-dichloro-3,5-dihydroimidazo[2,1-b]quinazolin-2(1H)-one
ethyl 2-((2,3-dichloro-6-nitrobenzyl)amino)acetate→ethyl 2-((6-amino-2,3-dichlorobenzyl)amino)acetate→aminomethyl propionate hydrochloride→ethyl 2-(5,6-dichloro-2-imino-1,2-dihydroquinazolin-3(4H)-yl)acetate hydrobromide→2,3-dichlorobenzaldehyde→2,3-dichloro-6-nitrobenzaldehyde
Intermediates available on this site
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