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CAS 85325-11-7
ethyl 2-((2,3-dichloro-6-nitrobenzyl)amino)acetate
Codes: ANAG-011
Application context (from source-drug indications)
Essential thrombocythaemiaAnagrelide Hydrochloride HydrateMyeloproliferative neoplasmAnagrelide Hydrochloride Hydrate血小板增多Anagrelide Hydrochloride HydrateMyelofibrosisAnagrelide Hydrochloride HydrateChronic myeloid leukaemiaAnagrelide Hydrochloride HydratePolycythaemia veraAnagrelide Hydrochloride Hydrate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Anagrelide Hydrochloride Hydrate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1,2,3-trichlorobenzene→1,2,3-trichlorobenzene→2,3-dichloro-6-nitrobenzonitrile→(2,3-dichloro-6-nitrophenyl)methanamine→ethyl 2-bromoacetate→ethyl 2-((2,3-dichloro-6-nitrobenzyl)amino)acetate→ethyl 2-((6-amino-2,3-dichlorobenzyl)amino)acetate→6,7-dichloro-3,5-dihydroimidazo[2,1-b]quinazolin-2(1H)-one hydrobromide
ethyl 2-((2,3-dichloro-6-nitrobenzyl)amino)acetate→ethyl 2-((6-amino-2,3-dichlorobenzyl)amino)acetate→aminomethyl propionate hydrochloride→ethyl 2-(5,6-dichloro-2-imino-1,2-dihydroquinazolin-3(4H)-yl)acetate hydrobromide→2,3-dichlorobenzaldehyde→2,3-dichloro-6-nitrobenzaldehyde
Intermediates available on this site
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