Unibest 优贝德
← Back to patent-cliff list

CAS 71989-33-8

Fmoc-O-tert-butyl-L-serine

Codes:Tirzepatide-001

Application context (from source-drug indications)

阻塞性睡眠呼吸暂停综合征替尔泊肽肥胖症替尔泊肽超重替尔泊肽二型糖尿病替尔泊肽

Source drugs (routes using this intermediate)

DrugTierExpiry
替尔泊肽TirzepatideTier B — Position early2036

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

替尔泊肽优化路线steps: 18total yield: /
Fmoc-O-tert-butyl-L-serine→Resin bound O-tert-butyl-L-serinamide→Resin bound L-prolyl-O-tert-butyl-L-serinamide→Resin bound L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound O-tert-butyl-L-seryl-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound Gly-Pro-Pro-Pro-Ser(tBu)-NH→Resin bound O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound L-prolyl-O-tert-butyl-L-seryl-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound glycyl-L-prolyl-O-tert-butyl-L-seryl-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound N-[(2,4-dimethoxyphenyl)methyl]glycylglycyl-L-prolyl-O-tert-butyl-L-seryl-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound L-alanyl-N-[(2,4-dimethoxyphenyl)methyl]glycylglycyl-L-prolyl-O-tert-butyl-L-seryl-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound L-isoleucyl-L-alanyl-N-[(2,4-dimethoxyphenyl)methyl]glycylglycyl-L-prolyl-O-tert-butyl-L-seryl-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound L-leucyl-L-isoleucyl-L-alanyl-N-[(2,4-dimethoxyphenyl)methyl]glycylglycyl-L-prolyl-O-tert-butyl-L-seryl-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound 1-(tert-butoxycarbonyl)-L-tryptophyl-L-leucyl-L-isoleucyl-L-alanyl-N-[(2,4-dimethoxyphenyl)methyl]glycylglycyl-L-prolyl-O-tert-butyl-L-seryl-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound N-(triphenylmethyl)-L-glutaminyl-1-(tert-butyloxycarbonyl)-L-tryptophyl-L-leucyl-L-isoleucyl-L-alanyl-N-[(2,4-dimethoxyphenyl)methyl]glycylglycyl-L-prolyl-3-O-tert-butyl-L-seryl-3-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound L-valyl-N-(triphenylmethyl)-L-glutaminyl-1-(tert-butyloxycarbonyl)-L-tryptophyl-L-leucyl-L-isoleucyl-L-alanyl-N-[(2,4-dimethoxyphenyl)methyl]glycylglycyl-L-prolyl-3-O-tert-butyl-L-seryl-3-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-3-O-tert-butyl-L-serinamide

Intermediates available on this site

Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.

SupplierProductPrice bandMOQLead timeQualifications
四川同晟生物医药有限公司Fmoc-Ser(tBu)-OH
Pharmaceutical Intermediates
询价询价询价
—

This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.