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CAS 808115-49-3
2-(1,3-dioxo-5-phenoxyisoindolin-2-yl)acetic acid
Codes：ROXA-003
Application context (from source-drug indications)
贫血罗沙司他
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 罗沙司他Roxadustat | Tier C — Watch / trade | 2028 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-phenoxyphthalic acid→2-aminoacetic acid→2-(1,3-dioxo-5-phenoxyisoindolin-2-yl)acetic acid→methyl 2-(1,3-dioxo-5-phenoxyisoindolin-2-yl)acetate→butyl 1,4-dihydroxy-7-phenoxyisoquinoline-3-carboxylate→butyl 1-bromo-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate→1-bromo-4-hydroxy-7-phenoxyisoquinoline-3-carboxylic acid→benzyl 4-(benzyloxy)-1-methyl-7-phenoxyisoquinoline-3-carboxylate→4-(benzyloxy)-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid→benzyl 2-aminoacetate hydrochloride→benzyl 2-(4-(benzyloxy)-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications |
|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | 4-hydroxy-1-methyl-7-phenoxy-3-Isoquinolinecarboxylic acid Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | 4-hydroxy-1-methyl-7-phenoxy-3-Isoquinolinecarboxylic acid Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | Methyl 4-hydroxy-7-phenoxyisoquinoline-3-carboxylate Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Taizhou GMP-like Site | 5-Phenoxyisobenzofuran-1(3H)-one Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | 4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid ethyl ester Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | 4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.