← Back to patent-cliff list
CAS 56-40-6
2-aminoacetic acid
Codes：ROXA-002
Application context (from source-drug indications)
贫血罗沙司他
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 罗沙司他Roxadustat | Tier C — Watch / trade | 2028 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-phenoxyphthalic acid→2-aminoacetic acid→2-(1,3-dioxo-5-phenoxyisoindolin-2-yl)acetic acid→methyl 2-(1,3-dioxo-5-phenoxyisoindolin-2-yl)acetate→butyl 1,4-dihydroxy-7-phenoxyisoquinoline-3-carboxylate→butyl 1-bromo-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate→1-bromo-4-hydroxy-7-phenoxyisoquinoline-3-carboxylic acid→benzyl 4-(benzyloxy)-1-methyl-7-phenoxyisoquinoline-3-carboxylate→4-(benzyloxy)-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid→benzyl 2-aminoacetate hydrochloride→benzyl 2-(4-(benzyloxy)-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate
2-aminoacetic acid→methyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate→phenol→5-bromoisobenzofuran-1(3H)-one→5-phenoxyisobenzofuran-1(3H)-one→2-(chloromethyl)-4-phenoxybenzoyl chloride→methyl 2-(chloromethyl)-4-phenoxybenzoate→methyl tosylglycinate→methyl 2-((N-(2-methoxy-2-oxoethyl)-4-methylphenylsulfonamido)methyl)-4-phenoxybenzoate→methyl 4-hydroxy-7-phenoxyisoquinoline-3-carboxylate→N,N,N',N'-tetramethylmethanediamine→methyl 1-((dimethylamino)methyl)-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate→methyl 1-(acetoxymethyl)-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications |
|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | 4-hydroxy-1-methyl-7-phenoxy-3-Isoquinolinecarboxylic acid Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | 4-hydroxy-1-methyl-7-phenoxy-3-Isoquinolinecarboxylic acid Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | Methyl 4-hydroxy-7-phenoxyisoquinoline-3-carboxylate Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Taizhou GMP-like Site | 5-Phenoxyisobenzofuran-1(3H)-one Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | 4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid ethyl ester Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | 4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.