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CAS 851452-97-6
5-(2-bromophenyl)-1-isobutyl-1H-imidazole-4-carboxylic acid
Codes: IMIQ-029
Application context (from source-drug indications)
Actinic keratosisImiquimod尖锐湿疣Imiquimod角化病ImiquimodBasal cell carcinomaImiquimod巨大尖锐湿疣Imiquimod人乳头瘤病毒感染Imiquimod
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Imiquimod | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-methylpropan-1-amine→4-chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline→ethyl 4-(piperazin-1-yl)benzoate→ethyl 2-isocyanoacetate→(Z)-ethyl 3-(2-bromophenyl)-2-formamidoacrylate→(E)-ethyl 3-bromo-3-(2-bromophenyl)-2-formamidoacrylate→(E)-ethyl 3-bromo-3-(2-bromophenyl)-2-isocyanoacrylate→ethyl 5-(2-bromophenyl)-1-isobutyl-1H-imidazole-4-carboxylate→5-(2-bromophenyl)-1-isobutyl-1H-imidazole-4-carboxylic acid→5-(2-bromophenyl)-1-isobutyl-1H-imidazole-4-carboxamide→1-isobutyl-1H-imidazo[4,5-c]quinolin-4(5H)-one
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