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CAS 872728-84-2

ethyl 3-(1-methyl-2-(((4-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)phenyl)amino)methyl)-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate

Codes:DABI-020

Application context (from source-drug indications)

静脉血栓栓塞达比加群酯甲磺酸盐栓塞达比加群酯甲磺酸盐中风达比加群酯甲磺酸盐缺血性卒中达比加群酯甲磺酸盐肺栓塞达比加群酯甲磺酸盐静脉血栓形成达比加群酯甲磺酸盐

Source drugs (routes using this intermediate)

DrugTierExpiry
达比加群酯甲磺酸盐Dabigatran Etexilate MesylateTier B — Position early-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

达比加群酯甲磺酸盐优化路线steps: 7total yield: 42 g
ethyl 3-(3-amino-4-(methylamino)-N-(pyridin-2-yl)benzamido)propanoate→hexyl carbonochloridate→4-aminobenzonitrile→(Z)-4-amino-N'-hydroxybenzimidamide→3-(4-aminophenyl)-1,2,4-oxadiazol-5(4H)-one→ethyl 2-bromoacetate→ethyl (4-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)phenyl)glycinate→(4-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)phenyl)glycine→ethyl 3-(1-methyl-2-(((4-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)phenyl)amino)methyl)-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate→ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate

Intermediates available on this site

Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.

SupplierProductPrice bandMOQLead timeQualifications
Qualified Partner — East China API WorksDabigatran etexilate mesylate
Pharmaceutical Intermediates
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Unibest Nantong cGMP Siteethyl N-[3-amino-4-(methylamino)benzoyl]-N-pyridin-2-yl-beta-alaninate
Pharmaceutical Intermediates
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Unibest Taizhou GMP-like SiteN-(4-cyanophenyl)-Glycine
Pharmaceutical Intermediates
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