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CAS 919475-15-3

2-[4-(benzyloxy)phenyl]-N,N-dimethylacetamide

Codes:Desvenlafaxine-006

Application context (from source-drug indications)

重度抑郁症地文拉法辛抑郁症地文拉法辛

Source drugs (routes using this intermediate)

DrugTierExpiry
地文拉法辛DesvenlafaxineTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

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地文拉法辛优化路线steps: 5total yield: /
2-[4-(benzyloxy)phenyl]acetic acid→2-[4-(benzyloxy)phenyl]acetyl chloride→2-[4-(benzyloxy)phenyl]-N,N-dimethylacetamide→Cyclohexanone→2-[4-(benzyloxy)phenyl]-2-(1-hydroxycyclohexyl)-N,N-dimethylacetamide→1-{1-[4-(Benzyloxy)phenyl]-2-(dimethylamino)ethyl}cyclohexan-1-ol

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