← Back to patent-cliff list
CAS 921-01-7
(S)-2-amino-3-mercaptopropanoic acid
Codes：ETEL-011
Application context (from source-drug indications)
继发性甲状旁腺功能亢进症盐酸依特卡肽慢性肾功能不全盐酸依特卡肽终末期肾脏病盐酸依特卡肽心源性水肿盐酸依特卡肽
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 盐酸依特卡肽Etelcalcetide Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(R)-2-amino-N-methyl-5-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentanamide→(R)-2-amino-N-methyl-5-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentanamide→(R)-2-((R)-2-aminopropanamido)-N-methyl-5-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentanamide→(R)-2-amino-N-((R)-1-(((R)-1-(methylamino)-1-oxo-5-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentan-2-yl)amino)-1-oxopropan-2-yl)-5-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentanamide→(R)-2-amino-N-((6R,9R,12R)-1,17-diimino-9-methyl-6-(methylcarbamoyl)-8,11-dioxo-1,17-bis(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonamido)-2,7,10,16-tetraazaheptadecan-12-yl)-5-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentanamide→(R)-2-amino-N-((6R,9R,12R,15R)-1,20-diimino-9-methyl-6-(methylcarbamoyl)-8,11,14-trioxo-1,20-bis(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonamido)-12-(3-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)propyl)-2,7,10,13,19-pentaazaicosan-15-yl)-5-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentanamide→(R)-2-((R)-2-aminopropanamido)-N-((6R,9R,12R,15R)-1,20-diimino-9-methyl-6-(methylcarbamoyl)-8,11,14-trioxo-1,20-bis(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonamido)-12-(3-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)propyl)-2,7,10,13,19-pentaazaicosan-15-yl)-5-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentanamide→(R)-2-((R)-2-((R)-2-amino-3-(tritylthio)propanamido)propanamido)-N-((6R,9R,12R,15R)-1,20-diimino-9-methyl-6-(methylcarbamoyl)-8,11,14-trioxo-1,20-bis(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonamido)-12-(3-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)propyl)-2,7,10,13,19-pentaazaicosan-15-yl)-5-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentanamide→(R)-2-((R)-2-((R)-2-acetamido-3-(tritylthio)propanamido)propanamido)-N-((6R,9R,12R,15R)-1,20-diimino-9-methyl-6-(methylcarbamoyl)-8,11,14-trioxo-1,20-bis(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonamido)-12-(3-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)propyl)-2,7,10,13,19-pentaazaicosan-15-yl)-5-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentanamide→(R)-2-((R)-2-((R)-2-acetamido-3-(pyridin-2-yldisulfanyl)propanamido)propanamido)-N-((6R,9R,12R,15R)-1,20-diamino-6-carbamoyl-12-(3-guanidinopropyl)-1,20-diimino-9-methyl-8,11,14-trioxo-2,7,10,13,19-pentaazaicosan-15-yl)-5-guanidinopentanamide→(S)-2-amino-3-mercaptopropanoic acid
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.