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CAS 34036-07-2

3,4-difluorobenzaldehyde

登记编号：TICA-031

应用背景（按来源药适应症）

中风替格瑞洛急性冠脉综合征替格瑞洛心肌梗塞替格瑞洛外周血管疾病替格瑞洛

来源药（使用该中间体的合成路线）

品种梯队到期年
替格瑞洛TicagrelorTier B · 提前布局2029

合成路线中的位置（上下游链）

按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。

替格瑞洛优化路线步数：7总收率：/
(1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine→3,4-difluorobenzaldehyde→malonic acid→(E)-3-(3,4-difluorophenyl)acrylic acid→(E)-3-(3,4-difluorophenyl)acryloyl chloride→(1R,2S,5R)-2-isopropyl-5-methylcyclohexan-1-ol→(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (E)-3-(3,4-difluorophenyl)acrylate→(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylate→(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid→(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carbonyl azide

本站可供应的对应中间体

同 CAS 多家在售供应横向对比；价格区间为供应方挂牌口径，实价以询价确认为准。

供应商产品价格区间最小起订货期资质
Qualified Partner — East China API Works4,6-Dichloro-2-(propylthio)pyrimidin -5-amine
Pharmaceutical Intermediates
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Unibest Nantong cGMP Site2-((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro -3aH-cyclopenta[d][1,3]dioxol -4-yloxy)ethanol L-tataric acid
Pharmaceutical Intermediates
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Unibest Taizhou GMP-like Site(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaminium(2R)hydroxy(phenyl)ethanoate
Pharmaceutical Intermediates
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Qualified Partner — East China API WorksEthanol, 2-[[(3aR,4S,6R,6aS)-6-[[5-aMino-6-chloro-2-(propylthio)-4-pyriMidinyl]aMino]tetrahydro-2,2-diMethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-
Pharmaceutical Intermediates
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Unibest Nantong cGMP Site(1R,2S)-2-(3,4-difluorophenyl)cyclopropanamine hydrochloride
Pharmaceutical Intermediates
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Unibest Taizhou GMP-like SiteCyclopropanamine,2-(3,4-difluorophenyl)-(1R,2S) -(2R,3R)-2,3-dihydroxybutanedioate (1:1)
Pharmaceutical Intermediates
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Qualified Partner — East China API Works2-[[(3aS,4R,6S,6aR)-4-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-6-yl]oxy]ethanol
Pharmaceutical Intermediates
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本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。