← 返回专利悬崖列表
CAS 5708-19-0
(S)-cyclohex-3-ene-1-carboxylic acid
登记编号：EDOX-002
应用背景（按来源药适应症）
肺栓塞甲苯磺酸艾多沙班静脉血栓栓塞甲苯磺酸艾多沙班中风甲苯磺酸艾多沙班栓塞甲苯磺酸艾多沙班静脉血栓形成甲苯磺酸艾多沙班缺血性卒中甲苯磺酸艾多沙班
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 甲苯磺酸艾多沙班Edoxaban Tosilate Hydrate | Tier B · 提前布局 | 2028 |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
cyclohex-3-ene-1-carboxylic acid→(S)-cyclohex-3-ene-1-carboxylic acid→(1S,4S,5S)-4-iodo-6-oxabicyclo[3.2.1]octan-7-one→ethyl (1S,3S,6R)-7-oxabicyclo[4.1.0]heptane-3-carboxylate→ethyl (1S,3R,4R)-3-azido-4-hydroxycyclohexane-1-carboxylate→ethyl (1S,3R,4R)-3-((tert-butoxycarbonyl)amino)-4-hydroxycyclohexane-1-carboxylate→ethyl (1S,3R,4S)-4-azido-3-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylate→(1S,3R,4S)-4-azido-3-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylic acid→tert-butyl ((1R,2S,5S)-2-azido-5-(dimethylcarbamoyl)cyclohexyl)carbamate→(1S,3R,4S)-3-amino-4-azido-N,N-dimethylcyclohexane-1-carboxamide→lithium 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylate→N-((1R,2S,5S)-2-azido-5-(dimethylcarbamoyl)cyclohexyl)-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide→N-((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide→sodium 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate
本站可供应的对应中间体
同 CAS 多家在售供应横向对比；价格区间为供应方挂牌口径，实价以询价确认为准。
| 供应商 | 产品 | 价格区间 | 最小起订 | 货期 | 资质 |
|---|---|---|---|---|---|
| Qualified Partner — East China API Works | (S)-cyclohex-3-enecarboxylic acid Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。