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CAS 76859-46-6
(4R,5S)-5-[(1S,2R)-2,4-Dihydroxy-1-methoxybutyl]-4-[(ethylsulfanyl)(methylsulfanyl)methyl]dihydrofuran-2(3H)-one
登记编号：Josamycin-011
应用背景（按来源药适应症）
细菌感染丙酸交沙霉素炎性疾病丙酸交沙霉素
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 丙酸交沙霉素Josamycin Propionate | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
(3aR,5S,6S,6aR)-5-[(4R)-2,2-Dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyltetrahydro-2H-furo[2,3-d][1,3]dioxol-6-ol→(3aS,5S,6R,6aS)-5-[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]-6-methoxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole→1,2-O-Isopropylidene-3-O-methyl-alpha-L-glucofuranose→6-O-Benzoyl-1,2-O-isopropylidene-3-O-methyl-alpha-L-glucofuranose→6-O-Benzoyl-1,2-O-isopropylidene-3-O-methyl-5-O-[(4-methylphenyl)sulfonyl]-alpha-L-glucofuranose→5-Deoxy-1,2-O-isopropylidene-3-O-methyl-alpha-L-xylo-hexofuranose→(Carbomethoxymethylene)triphenylphosphorane→Methyl (2E)-2,3,7-trideoxy-5-O-methyl-D-xylo-oct-2-enonate→Methyl (2E)-2,3,7-trideoxy-4,6-O-isopropylidene-8-O-(methoxymethyl)-5-O-methyl-D-xylo-oct-2-enonate→Methyl (4xi)-2,3,7-trideoxy-4,6-O-isopropylidene-8-O-(methoxymethyl)-5-O-methyl-3-[(methylsulfanyl)(methylsulfinyl)methyl]-D-lyxo-octonate→(4R,5S)-5-[(1S,2R)-2,4-Dihydroxy-1-methoxybutyl]-4-[(ethylsulfanyl)(methylsulfanyl)methyl]dihydrofuran-2(3H)-one→2,3,7-Trideoxy-3-[(ethylsulfanyl)(methylsulfanyl)methyl]-5-O-methyl-D-ido-octofuranose→Methyl 2,3,7-trideoxy-3-[(ethylsulfanyl)(methylsulfanyl)methyl]-5-O-methyl-D-ido-octofuranoside→Methyl 6,8-di-O-benzyl-2,3,7-trideoxy-3-[(ethylsulfanyl)(methylsulfanyl)methyl]-5-O-methyl-D-ido-octofuranoside→Methyl 6,8-di-O-benzyl-2,3,7-trideoxy-3-formyl-5-O-methyl-D-ido-octofuranoside
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