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CAS 1150618-39-5
tert-butyl (6-methylpiperidin-3-yl)carbamate
登记编号：PF-06651600-003
应用背景（按来源药适应症）
斑秃甲磺酸利特希替尼白癜风甲磺酸利特希替尼慢性荨麻疹甲磺酸利特希替尼化脓性汗腺炎甲磺酸利特希替尼瘢痕疙瘩甲磺酸利特希替尼乳糜泻甲磺酸利特希替尼
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 甲磺酸利特希替尼Ritlecitinib tosylate | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one→6-methylpyridin-3-amine→tert-butyl (6-methylpyridin-3-yl)carbamate→tert-butyl (6-methylpiperidin-3-yl)carbamate→benzyl 5-((tert-butoxycarbonyl)amino)-2-methylpiperidine-1-carboxylate→(2S,5R)-benzyl 5-((tert-butoxycarbonyl)amino)-2-methylpiperidine-1-carboxylate→(2S,5R)-benzyl 5-amino-2-methylpiperidine-1-carboxylate→2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine→(2S,5R)-benzyl 5-((2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidine-1-carboxylate→N-((3R,6S)-6-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine hydrochloride→1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one
本站可供应的对应中间体
同 CAS 多家在售供应横向对比；价格区间为供应方挂牌口径，实价以询价确认为准。
| 供应商 | 产品 | 价格区间 | 最小起订 | 货期 | 资质 |
|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | benzyl 5-amino-2-methylpiperidine-1-carboxylate Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | 5-AMino-2-Methyl-piperidine-1-carboxylic acid benzyl ester Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | benzyl(2S,5R)-5-amino-2-methylpiperidine-1-carboxylate Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Taizhou GMP-like Site | (R)-(-)-N-(3,5-DINITROBENZOYL)-ALPHA-PHENYLGLYCINE Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。