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CAS 172525-90-5
4'-((1,7'-dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carbaldehyde
登记编号：TELM-031
应用背景（按来源药适应症）
高血压替米沙坦/苯磺酸氨氯地平/氢氯噻嗪高血压瑞舒伐他汀钙/替米沙坦高脂血症瑞舒伐他汀钙/替米沙坦高血压苯磺酸氨氯地平/替米沙坦
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 替米沙坦/苯磺酸氨氯地平/氢氯噻嗪Telmisartan/Amlodipine Besylate/Hydrochlorothiazide | Tier C · 观察 / 贸易 | - |
| 瑞舒伐他汀钙/替米沙坦Rosuvastatin Calcium/Telmisartan | Tier C · 观察 / 贸易 | - |
| 苯磺酸氨氯地平/替米沙坦Amlodipine Besylate/Telmisartan | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
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1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzo[d]imidazole→4'-methyl-[1,1'-biphenyl]-2-carbonitrile→4'-(bromomethyl)-[1,1'-biphenyl]-2-carbonitrile→4'-(bromomethyl)-[1,1'-biphenyl]-2-carbaldehyde→4'-((1,7'-dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carbaldehyde
1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzo[d]imidazole→4'-methyl-[1,1'-biphenyl]-2-carbonitrile→4'-(bromomethyl)-[1,1'-biphenyl]-2-carbonitrile→4'-(bromomethyl)-[1,1'-biphenyl]-2-carbaldehyde→4'-((1,7'-dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carbaldehyde
1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzo[d]imidazole→4'-methyl-[1,1'-biphenyl]-2-carbonitrile→4'-(bromomethyl)-[1,1'-biphenyl]-2-carbonitrile→4'-(bromomethyl)-[1,1'-biphenyl]-2-carbaldehyde→4'-((1,7'-dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carbaldehyde
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