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CAS 17599-61-0
1,1,1-Trimethyl-N-[(E)-phenylmethylidene]silanamine
登记编号：(IV)140605-11-a
应用背景（按来源药适应症）
膀胱癌多西他赛纳米胶束 (Samyang Biopharmaceuticals)头颈癌多西他赛纳米胶束 (Samyang Biopharmaceuticals)头颈部鳞状细胞癌多西他赛纳米胶束 (Samyang Biopharmaceuticals)实体瘤多西他赛纳米胶束 (Samyang Biopharmaceuticals)
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 多西他赛纳米胶束 (Samyang Biopharmaceuticals)Docetaxel polymeric micelle (Samyang Biopharmaceuticals) | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
(4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-dicarboxylic acid→Ethyl glycolate→ethyl 2-{[(4R,5R)-5-[(2-ethoxy-2-oxoethoxy)carbonyl]-2,2-dimethyl-1,3-dioxolan-4-yl]carbonyloxy}acetate→1,1,1-Trimethyl-N-[(E)-phenylmethylidene]silanamine→4,5-bis(3R,4S)-2-oxo-4-phenylazetidin-3-yl (4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-dicarboxylate→4,5-bis(3R,4S)-1-[(tert-butoxy)carbonyl]-2-oxo-4-phenylazetidin-3-yl (4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-dicarboxylate→(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(acetyloxy)-1,15-dihydroxy-10,14,17,17-tetramethyl-11-oxo-9,12-bis[(triethylsilyl)oxy]-6-oxatetracyclo[11.3.1.0(3,10).0(4,7)]heptadec-13-en-2-yl benzoate→(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(acetyloxy)-15-{[(2R,3S)-2-{[(4R,5R)-5-({[(3S)-1-{[(1S,2S,3R,4S,7R,9S,10S,12S,15S)-4-(acetyloxy)-2-(benzoyloxy)-1-hydroxy-10,14,17,17-tetramethyl-11-oxo-9,12-bis[(triethylsilyl)oxy]-6-oxatetracyclo[11.3.1.0(3,10).0(4,7)]heptadec-13-en-15-yl]oxy}-3-{[(tert-butoxy)carbonyl]amino}-1-oxo-3-phenylpropan-2-yl]oxy}carbonyl)-2,2-dimethyl-1,3-dioxolan-4-yl]carbonyloxy}-3-{[(tert-butoxy)carbonyl]amino}-3-phenylpropanoyl]oxy}-1-hydroxy-10,14,17,17-tetramethyl-11-oxo-9,12-bis[(triethylsilyl)oxy]-6-oxatetracyclo[11.3.1.0(3,10).0(4,7)]heptadec-13-en-2-yl benzoate→(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1-hydroxy-10,14,17,17-tetramethyl-11-oxo-9,12-bis[(triethylsilyl)oxy]-6-oxatetracyclo[11.3.1.0(3,10).0(4,7)]heptadec-13-en-2-yl benzoate
本站可供应的对应中间体
目录暂未收录该靶点的在售中间体 —— 可直接发起询价，需求会进入撮合池。
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。