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CAS 178860-12-3
(4R)-4-(Acetyloxy)-1-[[(9H-fluoren-9-yl)methoxy]carbonyl]-L-proline
登记编号：ANID-036
应用背景（按来源药适应症）
念珠菌病阿尼芬净念珠菌血症阿尼芬净真菌感染阿尼芬净腹膜炎阿尼芬净脓肿阿尼芬净呼吸道感染阿尼芬净
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 阿尼芬净Anidulafungin | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
Resin bound N5-[O-acetyl-N-[[(9H-fluoren-9-yl)oxy]carbonyl]-L-threonyl-(3S,4S)-3-(acetyloxy)-4-methyl-L-prolyl]-(4R,5R)-4,5-bis(acetyloxy)-N2-(tert-butoxycarbonyl)-L-ornithine→(4S)-O-Acetyl-4-(acetyloxy)-4-[4-(acetyloxy)phenyl]-N-[[(9H-fluoren-9-yl)oxy]carbonyl]-L-threonine→Resin bound N5-[O-acetyl-N-[[(9H-fluoren-9-yl)methoxy]carbonyl]-L-threonyl-(4R)-4-(acetyloxy)-L-prolyl-(4S)-O-acetyl-4-(acetyloxy)-4-[4-(acetyloxy)phenyl]-L-threonyl-O-acetyl-L-threonyl-(3S,4S)-3-(acetyloxy)-4-methyl-L-prolyl]-(4R,5R)-4,5-bis(acetyloxy)-N2-(tert-butoxycarbonyl)-L-ornithine→Resin bound N5-[(4S)-O-acetyl-4-(acetyloxy)-4-[4-(acetyloxy)phenyl]-N-[[(9H-fluoren-9-yl)oxy]carbonyl]-L-threonyl-O-acetyl-L-threonyl-(3S,4S)-3-(acetyloxy)-4-methyl-L-prolyl]-(4R,5R)-4,5-bis(acetyloxy)-N2-(tert-butoxycarbonyl)-L-ornithine→(4R)-4-(Acetyloxy)-1-[[(9H-fluoren-9-yl)methoxy]carbonyl]-L-proline→Resin bound N5-[(4R)-4-(acetyloxy)-1-[[(9H-fluoren-9-yl)methoxy]carbonyl]-L-prolyl-(4S)-O-acetyl-4-(acetyloxy)-4-[4-(acetyloxy)phenyl]-L-threonyl-O-acetyl-L-threonyl-(3S,4S)-3-(acetyloxy)-4-methyl-L-prolyl]-(4R,5R)-4,5-bis(acetyloxy)-N2-(tert-butoxycarbonyl)-L-ornithine→O-Acetyl-N-[[(9H-fluoren-9-yl)methoxy]carbonyl]-L-threonine→N5-[O-Acetyl-L-threonyl-(4R)-4-(acetyloxy)-L-prolyl-(4S)-O-acetyl-4-(acetyloxy)-4-[4-(acetyloxy)phenyl]-L-threonyl-O-acetyl-L-threonyl-(3S,4S)-3-(acetyloxy)-4-methyl-L-prolyl]-(4R,5R)-4,5-bis(acetyloxy)-N2-(tert-butoxycarbonyl)-L-ornithine→(2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-6,20-Bis[(1R)-1-(acetyloxy)ethyl]-9-amino-23-[(1S,2S)-1,2-bis(acetyloxy)-2-[4-(acetyloxy)phenyl]ethyl]-16-methyl-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosine-2,11,12,15-tetrayl tetraacetate
本站可供应的对应中间体
同 CAS 多家在售供应横向对比；价格区间为供应方挂牌口径，实价以询价确认为准。
| 供应商 | 产品 | 价格区间 | 最小起订 | 货期 | 资质 |
|---|---|---|---|---|---|
| Qualified Partner — East China API Works | 4-(4'-Pentoxy-4-biphenylyl)benzoic acid Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | 1-(Diphenylmethyl)-3-hydroxyazetidine Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。