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CAS 769893-08-5
Methyl S-(acetamidomethyl)-L-cysteinyl-L-prolinate
登记编号：Atosiban-114
应用背景（按来源药适应症）
产科分娩（早产）阿托西班醋酸盐早产（孕37周前）阿托西班醋酸盐子宫内膜异位症阿托西班醋酸盐
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| 阿托西班醋酸盐Atosiban acetate | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
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Methyl S-(acetamidomethyl)-N-(tert-butoxycarbonyl)-L-cysteinyl-L-prolinate→Prop-2-en-1-yl S-(acetamidomethyl)-N-(tert-butoxycarbonyl)-L-cysteinyl-L-prolinate→Methyl S-(acetamidomethyl)-L-cysteinyl-L-prolinate→Prop-2-en-1-yl S-(acetamidomethyl)-L-cysteinyl-L-prolinate→N2-(tert-Butoxycarbonyl)-N-(triphenylmethyl)-L-asparagine→Methyl N2-(tert-butoxycarbonyl)-N-(triphenylmethyl)-L-asparaginyl-S-(acetamidomethyl)-L-cysteinyl-L-prolinate→Prop-2-en-1-yl N2-(ethoxycarbonyl)-N-(triphenylmethyl)-L-asparaginyl-S-(acetamidomethyl)-L-cysteinyl-L-prolinate→Trifluoroacetic acid methyl N-(triphenylmethyl)-L-asparaginyl-S-(acetamidomethyl)-L-cysteinyl-L-prolinate→Trifluoroacetic acid prop-2-en-1-yl N-(triphenylmethyl)-L-asparaginyl-S-(acetamidomethyl)-L-cysteinyl-L-prolinate→O-Ethyl-N-[3-[(triphenylmethyl)sulfanyl]propanoyl]-D-tyrosyl-L-isoleucyl-L-threonine→Methyl O-ethyl-N-[3-[(triphenylmethyl)sulfanyl]propanoyl]-D-tyrosyl-L-isoleucyl-L-threonyl-N-(triphenylmethyl)-L-asparaginyl-S-(acetamidomethyl)-L-cysteinyl-L-prolinate→Prop-2-en-1-yl O-ethyl-N-[3-[(triphenylmethyl)sulfanyl]propanoyl]-D-tyrosyl-L-isoleucyl-L-threonyl-N-(triphenylmethyl)-L-asparaginyl-S-(acetamidomethyl)-L-cysteinyl-L-prolinate→O-Ethyl-N-[3-[(triphenylmethyl)sulfanyl]propanoyl]-D-tyrosyl-L-isoleucyl-L-threonyl-N-(triphenylmethyl)-L-asparaginyl-S-(acetamidomethyl)-L-cysteinyl-L-proline
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