← 返回专利悬崖列表
CAS 97963-62-7
5-(Difluoromethoxy)-1H-benzimidazole-2-thiol
登记编号：S-pantoprazole sodium-017、S-pantoprazole sodium-050
应用背景（按来源药适应症）
胃食管反流病（S）-泮托拉唑钠消化性溃疡（S）-泮托拉唑钠出血（S）-泮托拉唑钠创伤和损伤（S）-泮托拉唑钠昏迷（S）-泮托拉唑钠吸入性肺炎（S）-泮托拉唑钠
来源药（使用该中间体的合成路线）
| 品种 | 梯队 | 到期年 |
|---|---|---|
| （S）-泮托拉唑钠S-pantoprazole sodium | Tier C · 观察 / 贸易 | - |
合成路线中的位置（上下游链）
按路线登记顺序排列，左→右为合成方向；高亮为当前 CAS，其余可点击跳转对应档案。
4-Acetamidophenol→Chlorodifluoromethane→N-[4-(Difluoromethoxy)phenyl]acetamide→N-[4-(Difluoromethoxy)-2-nitrophenyl]acetamide→2-(Chloromethyl)-3,4-dimethoxypyridine hydrogen chloride→4-(Difluoromethoxy)-2-nitroaniline→1,2-Diamino-4-(difluoromethoxy)benzene→O-Ethylxanthic acid potassium salt→5-(Difluoromethoxy)-1H-benzimidazole-2-thiol→5-(Difluoromethoxy)-2-(3,4-dimethoxypyridin-2-ylmethylsulfanyl)-1H-benzimidazole→(3,4-Dimethoxypyridin-2-yl)methanol
3-Hydroxy-2-methyl-4H-pyran-4-one→3-Methoxy-2-methyl-4H-pyran-4-one→3-Methoxy-2-methylpyridin-4-one→4-Chloro-3-methoxy-2-methylpyridine→5-(Difluoromethoxy)-1H-benzimidazole-2-thiol→4-Chloro-3-methoxy-2-methylpyridine 1-oxide→3,4-Dimethoxy-2-methylpyridine 1-oxide→(3,4-Dimethoxypyridin-2-yl)methanol→2-(Chloromethyl)-3,4-dimethoxypyridine hydrogen chloride→5-(Difluoromethoxy)-2-(3,4-dimethoxypyridin-2-ylmethylsulfanyl)-1H-benzimidazole→5-(Difluoromethoxy)-2-(3,4-dimethoxypyridin-2-ylmethylsulfinyl)-1H-benzimidazole
4-Acetamidophenol→Chlorodifluoromethane→N-[4-(Difluoromethoxy)phenyl]acetamide→N-[4-(Difluoromethoxy)-2-nitrophenyl]acetamide→N-[2-Amino-4-(difluoromethoxy)phenyl]acetamide→5-(Difluoromethoxy)-1H-benzimidazole-2-thiol→2-(Chloromethyl)-3,4-dimethoxypyridine hydrogen chloride→5-(Difluoromethoxy)-2-(3,4-dimethoxypyridin-2-ylmethylsulfanyl)-1H-benzimidazole
4-(Difluoromethoxy)-2-nitroaniline→1,2-Diamino-4-(difluoromethoxy)benzene→Carbon disulfide→5-(Difluoromethoxy)-1H-benzimidazole-2-thiol→2-(Chloromethyl)-3,4-dimethoxypyridine hydrogen chloride→2-(chloromethyl)-3,4-dimethoxypyridine→5-(Difluoromethoxy)-2-(3,4-dimethoxypyridin-2-ylmethylsulfanyl)-1H-benzimidazole→2-(Chloromethyl)-3,4-dimethoxy-1-oxo-1lambda5-pyridine→S-pantoprazole sodium-061
3-methoxy-2-methyl-4-nitro-1-oxido-1-pyridin-1-ylium→(3-methoxy-4-nitropyridin-2-yl)methyl methanesulfonate→5-(Difluoromethoxy)-1H-benzimidazole-2-thiol→5-(Difluoromethoxy)-2-(3,4-dimethoxypyridin-2-ylmethylsulfanyl)-1H-benzimidazole→4-Chloro-3-methoxy-2-methylpyridine 1-oxide→(4-chloro-3-methoxypyridin-2-yl)methyl methanesulfonate→2-[[(4-Chloro-3-methoxypyridin-2-yl)methyl]sulfanyl]-5-(difluoromethoxy)-1H-benzimidazole
2-(Chloromethyl)-3,4-dimethoxypyridine hydrogen chloride→5-(Difluoromethoxy)-1H-benzimidazole-2-thiol→5-(Difluoromethoxy)-2-(3,4-dimethoxypyridin-2-ylmethylsulfanyl)-1H-benzimidazole→(-)-(S)-Pantoprazole
本站可供应的对应中间体
目录暂未收录该靶点的在售中间体 —— 可直接发起询价，需求会进入撮合池。
本页为中间体 CAS 注册档案：同 CAS 的多条路线登记已合并；后续供应商报价与买方需求以该 CAS 为主键撮合。