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CAS 85-44-9
isobenzofuran-1,3-dione
Codes：LINA-015、TREL-014、ALOG-024
Application context (from source-drug indications)
二型糖尿病利格列汀二型糖尿病琥珀酸曲格列汀糖尿病琥珀酸曲格列汀二型糖尿病苯甲酸阿格列汀糖尿病苯甲酸阿格列汀急性冠脉综合征苯甲酸阿格列汀
Source drugs (routes using this intermediate)
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
8-bromo-7-(but-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione→2-(chloromethyl)-4-methylquinazoline→8-bromo-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione→1-(2-aminophenyl)ethan-1-one→2-chloroacetonitrile→(R)-2-(piperidin-3-yl)isoindoline-1,3-dione (2S,3S)-2,3-dihydroxysuccinate→(R)-7-(but-2-yn-1-yl)-8-(3-(1,3-dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione→pyridin-3-amine→piperidin-3-amine→isobenzofuran-1,3-dione→2-(piperidin-3-yl)isoindoline-1,3-dione→(2S,3S)-2,3-dihydroxysuccinic acid
2-(bromomethyl)-4-fluorobenzonitrile→6-chloro-3-methylpyrimidine-2,4(1H,3H)-dione→2-((6-chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile→(R)-piperidin-3-amine→(R)-2-(piperidin-3-yl)isoindoline-1,3-dione→(R)-2-((6-(3-(1,3-dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile→isobenzofuran-1,3-dione
6-chloro-3-methylpyrimidine-2,4(1H,3H)-dione→(R)-tert-butyl (1-(3,5-dimethyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yl)piperidin-3-yl)carbamate→2-((6-chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile→(R)-2-(piperidin-3-yl)isoindoline-1,3-dione→(R)-2-((6-(3-(1,3-dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile→(R)-piperidin-3-amine dihydrochloride→isobenzofuran-1,3-dione
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications |
|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | 3-Methylxanthine Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | 8-Bromo-3-methyl-3,9-dihydro-1H-purine-2,6-dione Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | 8-Bromo-7-(but-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Taizhou GMP-like Site | 2-(Chloromethyl)-4-methylquinazoline Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | 8-Bromo-7-(but-2-yn-1-yl)-3-methy1-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-dione Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | [(3R)-1-[7-(2-Butynyl)-2,3,6,7-tetrahydro-3-methy1-1-[(4-methy1-2-quinazolinyl)methyl]-2,6-dioxo-1H-purin-8-yll-3-piperidinyllcarbamicacid 1,1-dimethylethyl ester Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.