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拉替拉韦钾

Tier B — Position early

Raltegravir Potassium

默沙东
Originator
2007
First approval
-
Expiry (public)
$1.67B ▲
Peak sales
化学药
Type

Targets:HIV integrase

Brand:艾生特、Isentress

Indications (approved):HIV感染

Regional status

US
批准上市
2007-10-12
EU
批准上市
2007-12-19
China
批准上市
2009-03-31
Japan
批准上市
2008-06-24

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 11 · Total yield 91.5 g
Synthetic routes & intermediates Route 1
CodeCAS No.Intermediate
RALT-00175-86-52-hydroxy-2-methylpropanenitrile
RALT-00219355-69-22-amino-2-methylpropanenitrile
RALT-003100134-82-5benzyl (2-cyanopropan-2-yl)carbamate
RALT-004518047-98-8benzyl (Z)-(1-amino-1-(hydroxyimino)-2-methylpropan-2-yl)carbamate
RALT-005519032-08-7methyl 2-(2-(((benzyloxy)carbonyl)amino)propan-2-yl)-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylate
RALT-006888504-27-6methyl 2-(2-(((benzyloxy)carbonyl)amino)propan-2-yl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxylate
RALT-007140-75-0(4-fluorophenyl)methanamine
RALT-008518048-02-7benzyl (2-(4-((4-fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)carbamate
RALT-009518048-03-82-(2-aminopropan-2-yl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide
RALT-010889131-28-65-methyl-1,3,4-oxadiazole-2-carbonyl chloride
RALT-0114076-36-25-methyl-1H-tetrazole
RALT-0124755-77-5ethyl 2-chloro-2-oxoacetate
RALT-013-potassium 5-methyl-1,3,4-oxadiazole-2-carboxylate

Frequently asked questions

What are the approved indications of Raltegravir Potassium?

Approved indications include: HIV感染.

When does the Raltegravir Potassium patent expire?

No public expiry year is available for Raltegravir Potassium yet; this page updates once verified.

How many synthesis routes are recorded for Raltegravir Potassium?

1 synthesis routes are recorded; the shortest is 11 steps with 91.5 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Raltegravir Potassium intermediates?

All intermediates in Raltegravir Potassium routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Raltegravir Potassium intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-24