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CAS 4755-77-5
ethyl 2-chloro-2-oxoacetate
Codes：RALT-012
Application context (from source-drug indications)
HIV感染拉替拉韦钾硬化性胆管炎拉替拉韦钾HTLV-Ⅰ感染拉替拉韦钾慢性肾功能不全拉替拉韦钾复发-缓解型多发性硬化拉替拉韦钾高甘油三酯血症拉替拉韦钾
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 拉替拉韦钾Raltegravir Potassium | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-hydroxy-2-methylpropanenitrile→2-amino-2-methylpropanenitrile→benzyl (2-cyanopropan-2-yl)carbamate→benzyl (Z)-(1-amino-1-(hydroxyimino)-2-methylpropan-2-yl)carbamate→methyl 2-(2-(((benzyloxy)carbonyl)amino)propan-2-yl)-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylate→methyl 2-(2-(((benzyloxy)carbonyl)amino)propan-2-yl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxylate→(4-fluorophenyl)methanamine→benzyl (2-(4-((4-fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)carbamate→2-(2-aminopropan-2-yl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide→5-methyl-1,3,4-oxadiazole-2-carbonyl chloride→5-methyl-1H-tetrazole→ethyl 2-chloro-2-oxoacetate→potassium 5-methyl-1,3,4-oxadiazole-2-carboxylate
Intermediates available on this site
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