Pazufloxacin Mesylate
Tier C — Watch / tradePazufloxacin Mesylate
Targets：Topoisomerase IV, Bacterial DNA gyrase
Brand：Pasil, Pazucross
Indications (approved)：肺炎链球菌感染, Sepsis, Infectious disease, Cystitis, 胆管炎, Cholecystitis, Pulmonary tuberculosis, 肺脓肿
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| PAZU-001 | 122894-73-9 | ethyl 2,3,4,5-tetrafluorobenzoate |
| PAZU-002 | 541-16-2 | di-tert-butyl malonate |
| PAZU-003 | 123161-38-6 | 2-(4-(ethoxycarbonyl)-2,3,6-trifluorophenyl)acetic acid |
| PAZU-004 | 123161-40-0 | ethyl 4-(2-(benzhydryloxy)-2-oxoethyl)-2,3,5-trifluorobenzoate |
| PAZU-005 | 123161-41-1 | ethyl 4-(1-(benzhydryloxy)-3-hydroxy-1-oxopropan-2-yl)-2,3,5-trifluorobenzoate |
| PAZU-006 | 127045-52-7 | ethyl 4-(3-(benzhydryloxy)-3-oxoprop-1-en-2-yl)-2,3,5-trifluorobenzoate |
| PAZU-007 | 127045-58-3 | ethyl 4-(1-((benzhydryloxy)carbonyl)cyclopropyl)-2,3,5-trifluorobenzoate |
| PAZU-008 | 127045-61-8 | 1-(4-(ethoxycarbonyl)-2,3,6-trifluorophenyl)cyclopropane-1-carboxylic acid |
| PAZU-009 | 127045-64-1 | ethyl 4-(1-(((benzyloxy)carbonyl)amino)cyclopropyl)-2,3,5-trifluorobenzoate |
| PAZU-010 | 127045-73-2 | 4-(1-(((benzyloxy)carbonyl)amino)cyclopropyl)-2,3,5-trifluorobenzoic acid |
| PAZU-011 | 1071-46-1 | 3-ethoxy-3-oxopropanoic acid |
| PAZU-012 | 27045-79-8 | CAS |
| PAZU-013 | 35320-23-1 | (S)-2-aminopropan-1-ol |
| PAZU-014 | 127045-86-7 | ethyl (S,Z)-2-(4-(1-(((benzyloxy)carbonyl)amino)cyclopropyl)-2,3,5-trifluorobenzoyl)-3-((1-hydroxypropan-2-yl)amino)acrylate |
| PAZU-015 | 127046-03-1 | ethyl (S)-10-(1-(((benzyloxy)carbonyl)amino)cyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate |
| PAZU-016 | 127046-26-8 | (S)-10-(1-(((benzyloxy)carbonyl)amino)cyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid |
| PAZU-017 | 127046-45-1 | (S)-10-(1-aminocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride |
| Code | CAS No. | Intermediate |
|---|---|---|
| PAZU-013 | 35320-23-1 | (S)-2-aminopropan-1-ol |
| PAZU-018 | 1201-31-6 | 2,3,4,5-tetrafluorobenzoic acid |
| PAZU-019 | 1116-98-9 | tert-butyl 2-cyanoacetate |
| PAZU-020 | 143785-81-3 | ethyl 4-(2-(tert-butoxy)-1-cyano-2-oxoethyl)-2,3,5-trifluorobenzoate |
| PAZU-021 | 143785-82-4 | ethyl 4-(cyanomethyl)-2,3,5-trifluorobenzoate |
| PAZU-022 | 143785-83-5 | 4-(1-cyanocyclopropyl)-2,3,5-trifluorobenzoic acid |
| PAZU-023 | 143785-84-6 | 4-(1-carbamoylcyclopropyl)-2,3,5-trifluorobenzoic acid |
| PAZU-024 | 143785-86-8 | 4-(1-aminocyclopropyl)-2,3,5-trifluorobenzoic acid |
| PAZU-025 | 143785-87-9 | 4-(1-acetamidocyclopropyl)-2,3,5-trifluorobenzoic acid |
| PAZU-026 | 6148-64-7Available | potassium 3-ethoxy-3-oxopropanoate |
| PAZU-027 | 163680-78-2 | ethyl 3-(4-(1-acetamidocyclopropyl)-2,3,5-trifluorophenyl)-3-oxopropanoate |
| PAZU-028 | 163680-79-3 | ethyl (S)-2-(4-(1-acetamidocyclopropyl)-2,3,5-trifluorobenzoyl)-3-((1-hydroxypropan-2-yl)amino)acrylate |
| PAZU-029 | 127046-20-2 | ethyl (S)-10-(1-acetamidocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate |
| PAZU-030 | 163680-80-6 | (S)-10-(1-acetamidocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid |
| Code | CAS No. | Intermediate |
|---|---|---|
| PAZU-031 | 106939-34-8 | (S)-ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate |
| PAZU-032 | 105-56-6Available | ethyl 2-cyanoacetate |
| PAZU-033 | 479348-49-7 | ethyl (3S)-10-(1-cyano-2-ethoxy-2-oxoethyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate |
| PAZU-034 | 176760-98-8 | (S)-10-(cyanomethyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid |
| PAZU-035 | 176760-99-9 | (S)-10-(1-cyanocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid |
| PAZU-036 | 176761-00-5 | (S)-10-(1-carbamoylcyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid |
Frequently asked questions
What are the approved indications of Pazufloxacin Mesylate?
Approved indications include: 肺炎链球菌感染, Sepsis, Infectious disease, Cystitis, 胆管炎, Cholecystitis, Pulmonary tuberculosis, 肺脓肿.
When does the Pazufloxacin Mesylate patent expire?
No public expiry year is available for Pazufloxacin Mesylate yet; this page updates once verified.
How many synthesis routes are recorded for Pazufloxacin Mesylate?
3 synthesis routes are recorded; the shortest is 6 steps with 1.236 kg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Pazufloxacin Mesylate intermediates?
2 intermediate CAS of Pazufloxacin Mesylate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Pazufloxacin Mesylate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-27