芦卡帕利
Tier C — Watch / tradeRucaparib Camsylate
Targets：PARP-2、PARP-3、PARP1
Brand：Rubraca
Indications (approved)：前列腺癌、腹膜癌、卵巢上皮癌、输卵管癌、卵巢癌
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| RUCA-001 | 1122-91-4 | 4-bromobenzaldehyde |
| RUCA-002 | 1066-54-2 | ethynyltrimethylsilane |
| RUCA-003 | 77123-57-0 | 4-((trimethylsilyl)ethynyl)benzaldehyde |
| RUCA-004 | 880160-60-1 | N-methyl-1-(4-((trimethylsilyl)ethynyl)phenyl)methanamine |
| RUCA-005 | 880160-61-2 | methyl methyl(4-((trimethylsilyl)ethynyl)benzyl)carbamate |
| RUCA-006 | 880160-62-3 | methyl 4-ethynylbenzyl(methyl)carbamate |
| RUCA-007 | 880160-63-4 | methyl 5-fluoro-2-hydroxy-3-nitrobenzoate |
| RUCA-008 | 880160-64-5 | methyl 5-fluoro-2-((4-(((methoxycarbonyl)(methyl)amino)methyl)phenyl)ethynyl)-3-nitrobenzoate |
| RUCA-009 | 880160-65-6 | methyl 3-amino-5-fluoro-2-((4-(((methoxycarbonyl)(methyl)amino)methyl)phenyl)ethynyl)benzoate |
| RUCA-010 | 880160-66-7 | methyl 6-fluoro-2-(4-(((methoxycarbonyl)(methyl)amino)methyl)phenyl)-1H-indole-4-carboxylate |
| RUCA-011 | 73430-27-0 | (E)-N,N-dimethyl-2-nitroethenamine |
| RUCA-012 | 880160-67-8 | (E)-methyl 6-fluoro-2-(4-(((methoxycarbonyl)(methyl)amino)methyl)phenyl)-3-(2-nitrovinyl)-1H-indole-4-carboxylate |
| RUCA-013 | 880160-68-9 | methyl 6-fluoro-2-(4-(((methoxycarbonyl)(methyl)amino)methyl)phenyl)-3-(2-nitroethyl)-1H-indole-4-carboxylate |
| RUCA-014 | 880160-69-0 | methyl 4-(8-fluoro-6-oxo-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indol-2-yl)benzyl(methyl)carbamate |
| RUCA-015 | 345-16-4 | 5-fluoro-2-hydroxybenzoic acid |
| RUCA-016 | 391-92-4 | methyl 5-fluoro-2-hydroxybenzoate |
| Code | CAS No. | Intermediate |
|---|---|---|
| RUCA-017 | 78902-09-7 | 2-(2,2-diethoxyethyl)isoindoline-1,3-dione |
| RUCA-018 | 2913-97-5 | 2-(1,3-dioxoisoindolin-2-yl)acetaldehyde |
| RUCA-019 | 1082040-43-4Available | methyl 6-fluoro-1H-indole-4-carboxylate |
| RUCA-020 | 1408282-25-6 | methyl 3-(2-(1,3-dioxoisoindolin-2-yl)ethyl)-6-fluoro-1H-indole-4-carboxylate |
| RUCA-021 | 1408282-26-7Available | - |
| RUCA-022 | 283173-80-8 | - |
| RUCA-023 | 87199-17-5 | (4-formylphenyl)boronic acid |
| RUCA-024 | 283173-84-2 | 4-(8-fluoro-6-oxo-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indol-2-yl)benzaldehyde |
| RUCA-025 | 1424059-28-8 | (E)-8-fluoro-2-(4-((methylimino)methyl)phenyl)-4,5-dihydro-1H-azepino[5,4,3-cd]indol-6(3H)-one |
Frequently asked questions
What are the approved indications of Rucaparib Camsylate?
Approved indications include: 前列腺癌, 腹膜癌, 卵巢上皮癌, 输卵管癌, 卵巢癌.
When does the Rucaparib Camsylate patent expire?
No public expiry year is available for Rucaparib Camsylate yet; this page updates once verified.
How many synthesis routes are recorded for Rucaparib Camsylate?
2 synthesis routes are recorded; the shortest is 9 steps with 5.57 kg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Rucaparib Camsylate intermediates?
2 intermediate CAS of Rucaparib Camsylate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Rucaparib Camsylate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24