拉多替尼二盐酸盐
Tier C — Watch / tradeRadotinib Dihydrochloride
Targets：Bcr-Abl、PDGFR
Brand：Supect
Indications (approved)：慢性髓细胞白血病
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| RADO-001 | 41191-92-8 | ethyl 3-amino-4-methylbenzoate |
| RADO-002 | 641569-96-2Available | ethyl 3-guanidino-4-methylbenzoate nitrate |
| RADO-003 | 111781-53-4 | (E)-3-(dimethylamino)-1-(pyrazin-2-yl)prop-2-en-1-one |
| RADO-004 | 926038-04-2 | ethyl 4-methyl-3-((4-(pyrazin-2-yl)pyrimidin-2-yl)amino)benzoate |
| RADO-005 | 926038-16-6 | 4-methyl-3-((4-(pyrazin-2-yl)pyrimidin-2-yl)amino)benzoic acid |
| RADO-006 | 641571-11-1Available | 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline |
| RADO-007 | 54962-75-3 | 3-bromo-5-(trifluoromethyl)aniline |
| RADO-008 | 822-36-6 | 4-methyl-1H-imidazole |
| Code | CAS No. | Intermediate |
|---|---|---|
| RADO-009 | 926038-04-2 | ethyl 4-methyl-3-((4-(pyrazin-2-yl)pyrimidin-2-yl)amino)benzoate |
| RADO-010 | 641571-11-1Available | 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline |
Frequently asked questions
What are the approved indications of Radotinib Dihydrochloride?
Approved indications include: 慢性髓细胞白血病.
When does the Radotinib Dihydrochloride patent expire?
No public expiry year is available for Radotinib Dihydrochloride yet; this page updates once verified.
How many synthesis routes are recorded for Radotinib Dihydrochloride?
2 synthesis routes are recorded; the shortest is 1 steps with 18.7 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Radotinib Dihydrochloride intermediates?
2 intermediate CAS of Radotinib Dihydrochloride are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Radotinib Dihydrochloride intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24