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CAS 926038-16-6
4-methyl-3-((4-(pyrazin-2-yl)pyrimidin-2-yl)amino)benzoic acid
Codes：RADO-005
Application context (from source-drug indications)
慢性髓细胞白血病拉多替尼二盐酸盐费城染色体拉多替尼二盐酸盐髓系白血病慢性期拉多替尼二盐酸盐髓样白血病拉多替尼二盐酸盐帕金森病拉多替尼二盐酸盐白血病拉多替尼二盐酸盐
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 拉多替尼二盐酸盐Radotinib Dihydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
ethyl 3-amino-4-methylbenzoate→ethyl 3-guanidino-4-methylbenzoate nitrate→(E)-3-(dimethylamino)-1-(pyrazin-2-yl)prop-2-en-1-one→ethyl 4-methyl-3-((4-(pyrazin-2-yl)pyrimidin-2-yl)amino)benzoate→4-methyl-3-((4-(pyrazin-2-yl)pyrimidin-2-yl)amino)benzoic acid→3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline→3-bromo-5-(trifluoromethyl)aniline→4-methyl-1H-imidazole
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