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达诺瑞韦钠

Tier C — Watch / trade

Danoprevir Sodium

Array Biopharma
Originator
2018
First approval
-
Expiry (public)
$0.02B ▲
Peak sales
化学药
Type

TargetsNS3/NS4A

BrandGanovo、戈诺卫

Indications (approved)丙型肝炎

Regional status

US
无进展
2009-08-01
EU
无进展
2009-08-01
China
批准上市
2018-06-08
Japan
-

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 6 · Total yield /
Synthetic routes & intermediates Route 1
CodeCAS No.Intermediate
DANOP-001259214-56-7(1R,2S)-ethyl 1-amino-2-vinylcyclopropanecarboxylate hydrochloride
DANOP-00274844-91-01-(tert-butyl) 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
DANOP-003862119-82-2(2S,4R)-tert-butyl 2-(((1R,2S)-1-(ethoxycarbonyl)-2-vinylcyclopropyl)carbamoyl)-4-hydroxypyrrolidine-1-carboxylate
DANOP-004300831-21-4(S)-2-((tert-butoxycarbonyl)amino)non-8-enoic acid
DANOP-005552335-44-1(1R,2S)-ethyl 1-((2S,4R)-1-((S)-2-((tert-butoxycarbonyl)amino)non-8-enoyl)-4-hydroxypyrrolidine-2-carboxamido)-2-vinylcyclopropanecarboxylate
DANOP-0061884147-57-2(2R,6S,13aS,14aR,16aS,Z)-ethyl 6-((tert-butoxycarbonyl)amino)-2-hydroxy-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a-carboxylate
DANOP-007127168-78-91-(8-methoxy-4-(o-tolylamino)quinolin-3-yl)butan-1-one
DANOP-0081073069-02-9(2R,6S,13aS,14aR,16aS,Z)-ethyl 6-((tert-butoxycarbonyl)amino)-2-((4-fluoroisoindoline-2-carbonyl)oxy)-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a-carboxylate
DANOP-009850875-53-5(2R,6S,13aS,14aR,16aS,Z)-6-((tert-butoxycarbonyl)amino)-2-((4-fluoroisoindoline-2-carbonyl)oxy)-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a-carboxylic acid
DANOP-010154350-29-5cyclopropanesulfonamide

Frequently asked questions

What are the approved indications of Danoprevir Sodium?

Approved indications include: 丙型肝炎.

When does the Danoprevir Sodium patent expire?

No public expiry year is available for Danoprevir Sodium yet; this page updates once verified.

How many synthesis routes are recorded for Danoprevir Sodium?

1 synthesis routes are recorded; the shortest is 6 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Danoprevir Sodium intermediates?

All intermediates in Danoprevir Sodium routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Danoprevir Sodium intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-24