苯甲酸阿格列汀
Tier C — Watch / tradeAlogliptin Benzoate
Targets：DPP4
Brand：Vipidia、尼欣那、Nesina
Indications (approved)：二型糖尿病
Regional status
Synthetic routes & intermediates4 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| ALOG-001 | 4270-27-3Available | 6-chloropyrimidine-2,4(1H,3H)-dione |
| ALOG-002 | 22115-41-9Available | (R)-tert-butyl (1-(3,5-dimethyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yl)piperidin-3-yl)carbamate |
| ALOG-003 | 865758-95-8 | 2-((6-chloro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile |
| ALOG-004 | 865758-96-9Available | 2-((6-chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile |
| ALOG-005 | 334618-23-4Available | (R)-piperidin-3-amine dihydrochloride |
| ALOG-006 | 16682-12-5 | (R)-2,5-diaminopentanoic acid hydrochloride |
| ALOG-007 | 205598-55-6 | (R)-methyl 2,5-diaminopentanoate |
| ALOG-008 | 406216-02-2 | (R)-3-aminopiperidin-2-one hydrochloride |
| ALOG-009 | 943528-10-7 | (R)-piperidin-3-amine hydrochloride |
| Code | CAS No. | Intermediate |
|---|---|---|
| ALOG-010 | 1134529-25-1 | 2-(aminomethyl)benzonitrile hydrochloride |
| ALOG-011 | 1246610-71-8 | 1-(2-cyanobenzyl)-3-methylurea |
| ALOG-012 | 105-53-3Available | diethyl malonate |
| ALOG-013 | 1246610-72-9 | 2-((6-hydroxy-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile |
| ALOG-004 | 865758-96-9Available | 2-((6-chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile |
| ALOG-014 | 309956-78-3Available | (R)-tert-butyl piperidin-3-ylcarbamate |
| ALOG-015 | 1246610-74-1 | tert-butyl (R)-(1-(3-(2-cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)carbamate |
| Code | CAS No. | Intermediate |
|---|---|---|
| ALOG-016 | 344957-25-1 | 2-(aminomethyl)benzonitrile |
| ALOG-011 | 1246610-71-8 | 1-(2-cyanobenzyl)-3-methylurea |
| ALOG-017 | 372-09-8Available | 2-cyanoacetic acid |
| ALOG-018 | 1246610-78-5 | 2-cyano-N-((2-cyanobenzyl)carbamoyl)-N-methylacetamide |
| ALOG-019 | 1246610-77-4 | 2-((6-amino-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile |
| ALOG-020 | 1217656-59-1 | tert-butyl (R)-piperidin-3-ylcarbamate hydrochloride |
| ALOG-015 | 1246610-74-1 | tert-butyl (R)-(1-(3-(2-cyanobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidin-3-yl)carbamate |
| Code | CAS No. | Intermediate |
|---|---|---|
| ALOG-021 | 4318-56-3Available | 6-chloro-3-methylpyrimidine-2,4(1H,3H)-dione |
| ALOG-002 | 22115-41-9Available | (R)-tert-butyl (1-(3,5-dimethyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yl)piperidin-3-yl)carbamate |
| ALOG-004 | 865758-96-9Available | 2-((6-chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile |
| ALOG-022 | 886588-61-0 | (R)-2-(piperidin-3-yl)isoindoline-1,3-dione |
| ALOG-023 | 1430222-09-5 | (R)-2-((6-(3-(1,3-dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile |
| ALOG-005 | 334618-23-4Available | (R)-piperidin-3-amine dihydrochloride |
| ALOG-024 | 85-44-9Available | isobenzofuran-1,3-dione |
Frequently asked questions
What are the approved indications of Alogliptin Benzoate?
Approved indications include: 二型糖尿病.
When does the Alogliptin Benzoate patent expire?
No public expiry year is available for Alogliptin Benzoate yet; this page updates once verified.
How many synthesis routes are recorded for Alogliptin Benzoate?
4 synthesis routes are recorded; the shortest is 5 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Alogliptin Benzoate intermediates?
9 intermediate CAS of Alogliptin Benzoate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Alogliptin Benzoate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24