酒石酸长春氟宁
Tier C — Watch / tradeVinflunine Ditartrate
Targets：Tubulin
Brand：Javlor
Indications (approved)：泌尿系肿瘤、尿路上皮癌
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| VINF-001 | 71486-22-1 | methyl (3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-9-((6S,8S)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate |
| VINF-002 | 87-69-4 | (2R,3R)-2,3-dihydroxysuccinic acid |
| Code | CAS No. | Intermediate |
|---|---|---|
| VINF-001 | 71486-22-1 | methyl (3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-9-((6S,8S)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate |
| Code | CAS No. | Intermediate |
|---|---|---|
| VINF-003 | 113158-99-9 | methyl (6S)-7-ethyl-9,10,12,13-tetrahydro-5H-6,9-methanopyrido[1',2':1,2]azepino[4,5-b]indole-6(6aH)-carboxylate |
| VINF-004 | 60706-87-8 | dimethyl (6S)-7-ethyl-9,10,12,13-tetrahydro-5H-6,9-methanopyrido[1',2':1,2]azepino[4,5-b]indole-5,6(6aH)-dicarboxylate |
| VINF-005 | 60755-13-7 | dimethyl (6S)-7-ethyl-10-oxo-9,10,12,13-tetrahydro-5H-6,9-methanopyrido[1',2':1,2]azepino[4,5-b]indole-5,6(6aH)-dicarboxylate |
| VINF-006 | 1313860-86-4 | dimethyl (6S)-7-(1-hydroxyethyl)-10-oxo-9,10,12,13-tetrahydro-5H-6,9-methanopyrido[1',2':1,2]azepino[4,5-b]indole-5,6(6aH)-dicarboxylate |
| VINF-007 | 1012078-87-3 | dimethyl (6S)-7-acetyl-10-oxo-9,10,12,13-tetrahydro-5H-6,9-methanopyrido[1',2':1,2]azepino[4,5-b]indole-5,6(6aH)-dicarboxylate |
| VINF-008 | 1012078-92-0 | dimethyl (6S)-7-(1,1-difluoroethyl)-10-oxo-9,10,12,13-tetrahydro-5H-6,9-methanopyrido[1',2':1,2]azepino[4,5-b]indole-5,6(6aH)-dicarboxylate |
| VINF-009 | 1012078-88-4 | methyl (6S)-7-(1,1-difluoroethyl)-10-oxo-9,10,12,13-tetrahydro-5H-6,9-methanopyrido[1',2':1,2]azepino[4,5-b]indole-6(6aH)-carboxylate |
| VINF-010 | 1012078-81-7 | methyl (6S)-7-(1,1-difluoroethyl)-9,10,12,13-tetrahydro-5H-6,9-methanopyrido[1',2':1,2]azepino[4,5-b]indole-6(6aH)-carboxylate |
Frequently asked questions
What are the approved indications of Vinflunine Ditartrate?
Approved indications include: 泌尿系肿瘤, 尿路上皮癌.
When does the Vinflunine Ditartrate patent expire?
No public expiry year is available for Vinflunine Ditartrate yet; this page updates once verified.
How many synthesis routes are recorded for Vinflunine Ditartrate?
3 synthesis routes are recorded; the shortest is 1 steps with 3.43 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Vinflunine Ditartrate intermediates?
All intermediates in Vinflunine Ditartrate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Vinflunine Ditartrate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24