艾氟康唑
Tier C — Watch / tradeEfinaconazole
Targets：CYP51A1
Brand：Jublia/Clenafin、Jublia、Clenafin
Indications (approved)：甲癣
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| EFIN-001 | 17392-83-5Available | methyl (R)-2-hydroxypropanoate |
| EFIN-002 | 135206-87-0Available | (R)-2-hydroxy-1-morpholinopropan-1-one |
| EFIN-003 | 110-87-2 | 3,4-dihydro-2H-pyran |
| EFIN-004 | 135270-08-5Available | (2R)-1-morpholino-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one |
| EFIN-005 | 144025-04-7 | (2,4-difluorophenyl)magnesium bromide |
| EFIN-006 | 126918-17-0 | (2R)-1-(2,4-difluorophenyl)-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one |
| EFIN-007 | 288-88-0Available | 1H-1,2,4-triazole |
| EFIN-008 | 1175536-50-1 | (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol methanesulfonate |
| EFIN-009 | 127000-90-2 | 1-(((2R,3S)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole |
| EFIN-010 | 3522-98-3 | 4-methylenepiperidine hydrobromide |
| Code | CAS No. | Intermediate |
|---|---|---|
| EFIN-007 | 288-88-0Available | 1H-1,2,4-triazole |
| EFIN-009 | 127000-90-2 | 1-(((2R,3S)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole |
| EFIN-011 | 51336-94-8 | 2-chloro-1-(2,4-difluorophenyl)ethan-1-one |
| EFIN-012 | 7677-24-9 | trimethylsilanecarbonitrile |
| EFIN-013 | 454475-43-5 | (((2S,3S,4R)-4-(4,5-difluoro-2-hydroxyphenoxy)-3-hydroxytetrahydro-2H-pyran-2-yl)methyl)diphenylphosphine oxide |
| EFIN-014 | 861718-83-4 | (S)-3-chloro-2-(2,4-difluorophenyl)-2-((trimethylsilyl)oxy)propanenitrile |
| EFIN-015 | 861718-85-6 | (S)-3-chloro-2-(2,4-difluorophenyl)-2-((trimethylsilyl)oxy)propanal |
| EFIN-016 | 133775-25-4 | (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol |
| EFIN-017 | 148133-82-8 | 4-methylenepiperidine |
Frequently asked questions
What are the approved indications of Efinaconazole?
Approved indications include: 甲癣.
When does the Efinaconazole patent expire?
No public expiry year is available for Efinaconazole yet; this page updates once verified.
How many synthesis routes are recorded for Efinaconazole?
2 synthesis routes are recorded; the shortest is 5 steps with 67.6 mg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Efinaconazole intermediates?
4 intermediate CAS of Efinaconazole are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Efinaconazole intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24