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CAS 112-27-6
2,2'-(ethane-1,2-diylbis(oxy))bis(ethan-1-ol)
Codes：FLORB-001、ICOT-001
Application context (from source-drug indications)
阿尔茨海默病氟贝他吡[18F]造影检查氟贝他吡[18F]胶质母细胞瘤氟贝他吡[18F]神经变性疾病氟贝他吡[18F]额颞痴呆氟贝他吡[18F]轻度认知障碍氟贝他吡[18F]非小细胞肺癌盐酸埃克替尼肺腺癌盐酸埃克替尼支气管肿瘤盐酸埃克替尼肺癌盐酸埃克替尼转移性乳腺癌盐酸埃克替尼银屑病盐酸埃克替尼
Source drugs (routes using this intermediate)
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2,2'-(ethane-1,2-diylbis(oxy))bis(ethan-1-ol)→2-bromo-5-iodopyridine→2-(2-(2-((5-iodopyridin-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol→tert-butyl methyl(4-vinylphenyl)carbamate→tert-butyl (E)-(4-(2-(6-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)pyridin-3-yl)vinyl)phenyl)(methyl)carbamate→(E)-2-(2-(2-((5-(4-((tert-butoxycarbonyl)(methyl)amino)styryl)pyridin-2-yl)oxy)ethoxy)ethoxy)ethyl 4-methylbenzenesulfonate→4-vinylaniline→tert-butyl (4-vinylphenyl)carbamate
2,2'-(ethane-1,2-diylbis(oxy))bis(ethan-1-ol)→(ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate)→ethyl 3,4-dihydroxybenzoate→ethyl 2,3,5,6,8,9-hexahydrobenzo[b][1,4,7,10]tetraoxacyclododecine-12-carboxylate→ethyl 13-nitro-2,3,5,6,8,9-hexahydrobenzo[b][1,4,7,10]tetraoxacyclododecine-12-carboxylate→ethyl 13-amino-2,3,5,6,8,9-hexahydrobenzo[b][1,4,7,10]tetraoxacyclododecine-12-carboxylate hydrochloride→7,8,10,11,13,14-hexahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]quinazolin-4(3H)-one→4-chloro-7,8,10,11,13,14-hexahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]quinazoline→3-ethynylaniline
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