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CAS 1160182-44-4
4-bromo-3-(1,3-dioxolan-2-yl)phenol
Codes：CRISA-007
Application context (from source-drug indications)
特应性皮炎克立硼罗皮炎克立硼罗湿疹克立硼罗斑秃克立硼罗局部硬皮病克立硼罗斑块银屑病克立硼罗
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 克立硼罗Crisaborole | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-(4-bromo-3-formylphenoxy)benzonitrile→2-bromo-5-hydroxybenzaldehyde→ethane-1,2-diol→4-bromo-3-(1,3-dioxolan-2-yl)phenol→4-fluorobenzonitrile
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications |
|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | 2-BROMO-5-HYDROXYBENZALDEHYDE Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | 4-(4-Bromo-3-formyl-phenoxy)-benzonitrile Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Nantong cGMP Site | 4-[4-bromo-3-(hydroxymethyl)phenoxy]benzonitrile Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Unibest Taizhou GMP-like Site | [2-bromo-5-(4-cyanophenoxy)phenyl]methyl acetate Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.