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CAS 119141-88-7

(S)-5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole

Codes: ESOME-006

Application context (from source-drug indications)

HeartburnEsomeprazole Magnesium HydrateGastro-oesophageal reflux diseaseEsomeprazole Magnesium HydrateDuodenal ulcerEsomeprazole Magnesium HydrateGastric ulcerEsomeprazole Magnesium HydratePeptic oesophagitisEsomeprazole Magnesium HydrateHelicobacter pylori infectionEsomeprazole Magnesium Hydrate

Source drugs (routes using this intermediate)

DrugTierExpiry
Esomeprazole Magnesium HydrateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Esomeprazole Magnesium HydrateOptimised routesteps: 5total yield: 18.00 g
5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole→(S)-5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole→sodium 5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide→diethyl (2S,3S)-2,3-dihydroxysuccinate→sodium (R)-5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)(methyl)(oxo)-l5-sulfanyl)benzo[d]imidazol-1-ide→ESOME-011

Intermediates available on this site

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