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CAS 1376112-92-3
(3S,5R)-benzyl 3-hydroxy-5-((4-methoxybenzyl)oxy)hexadecanoate
Codes: ORLI-078
Application context (from source-drug indications)
ObesityOrlistatI型高脂蛋白血症OrlistatHypertriglyceridaemiaOrlistat女性不孕OrlistatDiabetesOrlistatObstructive sleep apnoea syndromeOrlistat
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Orlistat | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(3S,4S)-3-hexyl-4-((R)-2-hydroxytridecyl)oxetan-2-one→(S)-2-formamido-4-methylpentanoic acid→1-iodohexane→dodecanal→ethynyltrimethylsilane→1-(trimethylsilyl)tetradec-1-yn-3-ol→tetradec-1-yn-3-ol→(S)-2-phenyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole→(R)-tetradec-1-yn-3-ol→(R)-1-methoxy-4-((tetradec-1-yn-3-yloxy)methyl)benzene→benzo[d][1,3,2]dioxaborole→(R)-3-((4-methoxybenzyl)oxy)tetradecanal→((1-(benzyloxy)vinyl)oxy)(tert-butyl)dimethylsilane→(3S,5R)-benzyl 3-hydroxy-5-((4-methoxybenzyl)oxy)hexadecanoate→(2S,3S,5R)-benzyl 2-hexyl-3-hydroxy-5-((4-methoxybenzyl)oxy)hexadecanoate→(2S,3S,5R)-2-hexyl-3-hydroxy-5-((4-methoxybenzyl)oxy)hexadecanoic acid→2-methyl-6-nitrobenzoic anhydride→(3S,4S)-3-hexyl-4-((R)-2-((4-methoxybenzyl)oxy)tridecyl)oxetan-2-one
Intermediates available on this site
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