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CAS 13790-39-1
4-chloro-6,7-dimethoxyquinazoline
Codes：ICOT-012
Application context (from source-drug indications)
非小细胞肺癌盐酸埃克替尼肺腺癌盐酸埃克替尼支气管肿瘤盐酸埃克替尼肺癌盐酸埃克替尼转移性乳腺癌盐酸埃克替尼银屑病盐酸埃克替尼
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 盐酸埃克替尼Icotinib Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate)→2-amino-4,5-dimethoxybenzoic acid→6,7-dimethoxyquinazolin-4(3H)-one→4-chloro-6,7-dimethoxyquinazoline→3-bromoaniline→N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine→4-((3-bromophenyl)amino)quinazoline-6,7-diol hydrochloride→N-(3-bromophenyl)-7,8,10,11,13,14-hexahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]quinazolin-4-amine→ethynyltrimethylsilane
Intermediates available on this site
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| Supplier | Product | Price band | MOQ | Lead time | Qualifications |
|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | 4-Chloro-6,7-dimethoxyquinazoline Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
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