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CAS 147357-20-8
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-, 3-ethyl 5-methyl ester
Codes：Levamlodipine Besylate-019
Application context (from source-drug indications)
高血压苯磺酸左旋氨氯地平心绞痛苯磺酸左旋氨氯地平原发性高血压苯磺酸左旋氨氯地平
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 苯磺酸左旋氨氯地平Levamlodipine Besylate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-, 3-ethyl 5-methyl ester→3-ethyl 5-methyl 4-bromo-2-(bromomethyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate→N-Hydroxyethylphthalimide→3-ethyl 5-methyl 4-bromo-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate→2-Chlorophenylboronic acid→Phthaloyl amlodipine→(±)-2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine
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