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CAS 3900-89-8
(o-Chlorophenyl)boronic acid2-Chlorophenylboronic acid
Codes：(V)270899-3-a、Levamlodipine Besylate-023
Application context (from source-drug indications)
重度抑郁症盐酸艾司氯胺酮自杀意念盐酸艾司氯胺酮抑郁症盐酸艾司氯胺酮麻醉盐酸艾司氯胺酮难治性抑郁症盐酸艾司氯胺酮疼痛盐酸艾司氯胺酮高血压苯磺酸左旋氨氯地平心绞痛苯磺酸左旋氨氯地平原发性高血压苯磺酸左旋氨氯地平
Source drugs (routes using this intermediate)
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-Hydroxycyclohex-2-en-1-one→3-Bromo-2-hydroxycyclohex-2-en-1-one→3-Bromo-2-methoxycyclohex-2-en-1-one→2-Methoxycyclohex-2-en-1-one→(o-Chlorophenyl)boronic acid→2'-Chloro-2-methoxy-5,6-dihydro[1,1'-biphenyl]-3(4H)-one→(3S)-2'-Chloro-2-methoxy-3,4,5,6-tetrahydro[1,1'-biphenyl]-3-ol→2,2,2-Trichloro-N-(oxomethylidene)acetamide→(3S)-2'-Chloro-2-methoxy-3,4,5,6-tetrahydro[1,1'-biphenyl]-3-yl carbamate→(1S)-2'-Chloro-1-isocyanato-6-methoxy-1,2,3,4-tetrahydro-1,1'-biphenyl→(1S)-2'-Chloro-6-methoxy-N-methyl-3,4-dihydro[1,1'-biphenyl]-1(2H)-amine
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-, 3-ethyl 5-methyl ester→3-ethyl 5-methyl 4-bromo-2-(bromomethyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate→N-Hydroxyethylphthalimide→3-ethyl 5-methyl 4-bromo-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate→2-Chlorophenylboronic acid→Phthaloyl amlodipine→(±)-2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine
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