CAS 147962-41-2

Codes：MACI-019

Application context (from source-drug indications)

肺动脉高压马昔腾坦肺性高血压马昔腾坦慢性病马昔腾坦慢性血栓栓塞性肺高压马昔腾坦血栓栓塞马昔腾坦心绞痛马昔腾坦

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
马昔腾坦Macitentan	Tier B — Position early	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

马昔腾坦优化路线steps: 4total yield: 225 g

5-(4-bromophenyl)-4,6-dichloropyrimidine→MACI-009→MACI-011→5-bromo-2-chloropyrimidine→sulfurisocyanatidic chloride→propan-1-amine→MACI-019→2-(tert-butoxy)ethanol

Intermediates available on this site

No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.

This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.