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CAS 154235-77-5

benzo[d]oxazole-6-carboxylic acid

CodesTAFA-006

Application context (from source-drug indications)

淀粉样多神经病氯苯唑酸葡甲胺转甲状腺素运载蛋白淀粉样变性氯苯唑酸葡甲胺淀粉样变氯苯唑酸葡甲胺心肌疾病氯苯唑酸葡甲胺淀粉体轻链淀粉样变性氯苯唑酸葡甲胺家族性淀粉样神经病氯苯唑酸葡甲胺

Source drugs (routes using this intermediate)

DrugTierExpiry
氯苯唑酸葡甲胺Tafamidis MeglumineTier B — Position early-

Position in synthesis routes (up/downstream chain)

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氯苯唑酸葡甲胺优化路线steps: 4total yield: 24.7 mg
4-amino-3-hydroxybenzoic acidbenzo[d]oxazole-6-carboxylic acidbenzo[d]oxazol-6-yl(morpholino)methanone1,3-dichloro-5-iodobenzene(2-(3,5-dichlorophenyl)benzo[d]oxazol-6-yl)(morpholino)methanone

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