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CAS 1810713-73-5
N-Boc-[1(S)-(3-Methoxyphenyl)ethyl]-N-methylamine
Codes: (XVI)145089-2-a,(XVI)145089-2-d
Application context (from source-drug indications)
Alzheimer's diseaseRivastigmine TartrateDementiaRivastigmine TartrateParkinson's diseaseRivastigmine Tartrate抗胆碱能综合征Rivastigmine Tartrate神经行为学表现Rivastigmine TartrateCognitive impairmentRivastigmine Tartrate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Rivastigmine Tartrate | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(3-Hydroxyphenyl)ethanone→1-(3-Methoxyphenyl)ethanone→(1E)-1-(3-Methoxyphenyl)ethanone oxime→1-(3-Methoxyphenyl)ethanamine→1(S)-(3-Methoxyphenyl)ethylamine 2(S)-hydroxy-2-phenylacetate→1(S)-(3-Methoxyphenyl)-N,N-dimethylethylamine→(-)-3-((1S)-1-(Dimethylamino)ethyl)phenol→Potassium 3-[(1S)-1-(dimethylamino)ethyl]phenolate→N-Ethyl-N-methylcarbamic chloride→Ethyl(methyl)carbamic bromide→(S)-3-(1-(Dimethylamino)ethyl)phenyl ethyl(methyl)carbamate→1(R)-(3-Methoxyphenyl)-N,N-dimethylethylamine 2(S)-hydroxy-2-phenylacetate→1(R)-(3-Methoxyphenyl)-N,N-dimethylethylamine→(1R)-1-(3-Methoxyphenyl)ethanol→(1R)-1-(3-Methoxyphenyl)ethyl methanesulfonate→Dimethylamine anhydrous→N-[(1Z)-1-(3-Methoxyphenyl)ethylidene]methanamine→N-Boc-[1(S)-(3-Methoxyphenyl)ethyl]-N-methylamine
N-Boc-[1(S)-(3-Methoxyphenyl)ethyl]-N-methylamine→(3aS,7aS)-2-[(E)-[(3-Methoxyphenyl)methylidene]amino]-1,3-di(propan-2-yl)octahydro-1H-1,3,2lambda5-benzodiazaphosphol-2-one→Iodo(methyl)magnesium→(3aS,7aS)-2-[[(1S)-1-(3-Methoxyphenyl)ethyl]amino]-1,3-di(propan-2-yl)octahydro-1H-1,3,2lambda5-benzodiazaphosphol-2-one→N-Boc-1(S)-(3-Methoxyphenyl)ethanamine→Iodomethane
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