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CAS 218900-56-2

N-Boc-1(S)-(3-Methoxyphenyl)ethanamine

Codes: (XXXII)145089-2-d

Application context (from source-drug indications)

Alzheimer's diseaseRivastigmine TartrateDementiaRivastigmine TartrateParkinson's diseaseRivastigmine Tartrate抗胆碱能综合征Rivastigmine Tartrate神经行为学表现Rivastigmine TartrateCognitive impairmentRivastigmine Tartrate

Source drugs (routes using this intermediate)

DrugTierExpiry
Rivastigmine TartrateTier B — Position early-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Rivastigmine TartrateOptimised routesteps: 3total yield: /
N-Boc-[1(S)-(3-Methoxyphenyl)ethyl]-N-methylamine→(3aS,7aS)-2-[(E)-[(3-Methoxyphenyl)methylidene]amino]-1,3-di(propan-2-yl)octahydro-1H-1,3,2lambda5-benzodiazaphosphol-2-one→Iodo(methyl)magnesium→(3aS,7aS)-2-[[(1S)-1-(3-Methoxyphenyl)ethyl]amino]-1,3-di(propan-2-yl)octahydro-1H-1,3,2lambda5-benzodiazaphosphol-2-one→N-Boc-1(S)-(3-Methoxyphenyl)ethanamine→Iodomethane

Intermediates available on this site

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