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CAS 214403-86-8
(1H-imidazol-1-yl)phosphonic (((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphoric) anhydride
Codes：DIQU-004
Application context (from source-drug indications)
干眼症地夸磷索钠干眼综合征地夸磷索钠干燥性角结膜炎地夸磷索钠
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 地夸磷索钠Diquafosol Tetrasodium | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
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((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen diphosphate→1H-imidazole→(1H-imidazol-1-yl)phosphonic (((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphoric) anhydride
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