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CAS 23031-78-9
benzo[d]isothiazol-3-amine
Codes：LURA-022
Application context (from source-drug indications)
重度抑郁症盐酸鲁拉西酮精神分裂症盐酸鲁拉西酮躁狂症盐酸鲁拉西酮抑郁症盐酸鲁拉西酮
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 盐酸鲁拉西酮Lurasidone Hydrochloride | Tier B — Position early | 2028 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(3aR,4S,7R,7aS)-hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione→((1R,2R)-cyclohexane-1,2-diyl)bis(methylene) dimethanesulfonate→2,2'-azanediylbis(ethan-1-ol)→((1R,2R)-2-((bis(2-hydroxyethyl)amino)methyl)cyclohexyl)methyl methanesulfonate→(3aR,4S,7R,7aS)-2-(((1R,2R)-2-((bis(2-hydroxyethyl)amino)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione→((((1R,2R)-2-(((3aR,4S,7R,7aS)-1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl)methyl)cyclohexyl)methyl)azanediyl)bis(ethane-2,1-diyl) dimethanesulfonate→benzo[d]isothiazol-3-amine
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