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CAS 111-42-2
2,2'-azanediylbis(ethan-1-ol)
Codes：LURA-018、RANO-010
Application context (from source-drug indications)
重度抑郁症盐酸鲁拉西酮精神分裂症盐酸鲁拉西酮躁狂症盐酸鲁拉西酮抑郁症盐酸鲁拉西酮心绞痛雷诺嗪心肌梗塞雷诺嗪肌萎缩性侧索硬化雷诺嗪稳定型心绞痛雷诺嗪克罗恩病雷诺嗪炎症性肠疾病雷诺嗪
Source drugs (routes using this intermediate)
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(3aR,4S,7R,7aS)-hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione→((1R,2R)-cyclohexane-1,2-diyl)bis(methylene) dimethanesulfonate→2,2'-azanediylbis(ethan-1-ol)→((1R,2R)-2-((bis(2-hydroxyethyl)amino)methyl)cyclohexyl)methyl methanesulfonate→(3aR,4S,7R,7aS)-2-(((1R,2R)-2-((bis(2-hydroxyethyl)amino)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione→((((1R,2R)-2-(((3aR,4S,7R,7aS)-1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl)methyl)cyclohexyl)methyl)azanediyl)bis(ethane-2,1-diyl) dimethanesulfonate→benzo[d]isothiazol-3-amine
2-chloroacetyl chloride→2,6-dimethylaniline→2-chloro-N-(2,6-dimethylphenyl)acetamide→2-((2-methoxyphenoxy)methyl)oxirane→2-methoxyphenol→2-(chloromethyl)oxirane→2,2'-azanediylbis(ethan-1-ol)→2-(bis(2-hydroxyethyl)amino)-N-(2,6-dimethylphenyl)acetamide→2-(bis(2-chloroethyl)amino)-N-(2,6-dimethylphenyl)acetamide→1-amino-3-(2-methoxyphenoxy)propan-2-ol
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