CAS 23500-10-9

(2-chloroacetyl)-L-proline

Codes：VILD-010

Application context (from source-drug indications)

二型糖尿病维格列汀精神分裂症维格列汀血脂障碍维格列汀胰岛素抵抗维格列汀一型糖尿病维格列汀糖尿病维格列汀

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
维格列汀Vildagliptin	Tier B — Position early	-

Position in synthesis routes (up/downstream chain)

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维格列汀优化路线steps: 3total yield: /

2-chloroacetyl chloride→(S)-1-(2-chloroacetyl)pyrrolidine-2-carboxamide→(S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile→(S)-pyrrolidine-2-carboxylic acid→(2-chloroacetyl)-L-proline

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