维格列汀
Tier B — Position earlyVildagliptin
Targets：DPP4
Brand：Galvus、Jalra、Gliptus、佳维乐、Equa、Xiliarx
Indications (approved)：二型糖尿病
Regional status
Synthetic routes & intermediates6 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| VILD-001 | 7531-52-4 | (S)-pyrrolidine-2-carboxamide |
| VILD-002 | 79-04-9Available | 2-chloroacetyl chloride |
| VILD-003 | 214398-99-9 | (S)-1-(2-chloroacetyl)pyrrolidine-2-carboxamide |
| VILD-004 | 3724-43-4Available | N-(chloromethylene)-N-methylmethanaminium chloride |
| VILD-005 | 207557-35-5 | (S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile |
| VILD-006 | 702-82-9 | (1s,3r,5R,7S)-3-aminoadamantan-1-ol |
| VILD-007 | 768-94-5 | (3s,5s,7s)-adamantan-1-amine |
| VILD-008 | 243145-00-8 | (1r,3s,5R,7S)-3-nitroadamantan-1-amine |
| Code | CAS No. | Intermediate |
|---|---|---|
| VILD-002 | 79-04-9Available | 2-chloroacetyl chloride |
| VILD-003 | 214398-99-9 | (S)-1-(2-chloroacetyl)pyrrolidine-2-carboxamide |
| VILD-005 | 207557-35-5 | (S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile |
| VILD-009 | 147-85-3 | (S)-pyrrolidine-2-carboxylic acid |
| VILD-010 | 23500-10-9 | (2-chloroacetyl)-L-proline |
| Code | CAS No. | Intermediate |
|---|---|---|
| VILD-001 | 7531-52-4 | (S)-pyrrolidine-2-carboxamide |
| VILD-006 | 702-82-9 | (1s,3r,5R,7S)-3-aminoadamantan-1-ol |
| VILD-011 | 665-66-7 | (3s,5s,7s)-adamantan-1-amine hydrochloride |
| VILD-012 | 5292-43-3 | tert-butyl 2-bromoacetate |
| VILD-013 | 1334337-68-6 | tert-butyl ((1r,3s,5R,7S)-3-hydroxyadamantan-1-yl)glycinate |
| VILD-014 | 1032564-18-3 | ((1r,3s,5R,7S)-3-hydroxyadamantan-1-yl)glycine |
| VILD-015 | 204387-53-1 | (S)-pyrrolidine-2-carbonitrile |
| VILD-016 | 2133-40-6 | methyl L-prolinate hydrochloride |
| Code | CAS No. | Intermediate |
|---|---|---|
| VILD-001 | 7531-52-4 | (S)-pyrrolidine-2-carboxamide |
| VILD-011 | 665-66-7 | (3s,5s,7s)-adamantan-1-amine hydrochloride |
| VILD-012 | 5292-43-3 | tert-butyl 2-bromoacetate |
| VILD-014 | 1032564-18-3 | ((1r,3s,5R,7S)-3-hydroxyadamantan-1-yl)glycine |
| VILD-015 | 204387-53-1 | (S)-pyrrolidine-2-carbonitrile |
| VILD-016 | 2133-40-6 | methyl L-prolinate hydrochloride |
| VILD-017 | 924281-70-9 | tert-butyl ((3s,5s,7s)-adamantan-1-yl)glycinate |
| VILD-018 | 16782-41-5 | ((3s,5s,7s)-adamantan-1-yl)glycine |
| VILD-019 | 35150-07-3 | tert-butyl (S)-2-carbamoylpyrrolidine-1-carboxylate |
| Code | CAS No. | Intermediate |
|---|---|---|
| VILD-006 | 702-82-9 | (1s,3r,5R,7S)-3-aminoadamantan-1-ol |
| VILD-011 | 665-66-7 | (3s,5s,7s)-adamantan-1-amine hydrochloride |
| VILD-014 | 1032564-18-3 | ((1r,3s,5R,7S)-3-hydroxyadamantan-1-yl)glycine |
| VILD-015 | 204387-53-1 | (S)-pyrrolidine-2-carbonitrile |
| VILD-020 | 298-12-4Available | 2-oxoacetic acid |
| VILD-021 | 1334337-69-7 | (E)-2-(((1r,3s,5R,7S)-3-hydroxyadamantan-1-yl)imino)acetic acid |
| Code | CAS No. | Intermediate |
|---|---|---|
| VILD-001 | 7531-52-4 | (S)-pyrrolidine-2-carboxamide |
| VILD-006 | 702-82-9 | (1s,3r,5R,7S)-3-aminoadamantan-1-ol |
| VILD-020 | 298-12-4Available | 2-oxoacetic acid |
| VILD-022 | 1354835-81-6 | N-formyl-N-((1r,3s,5R,7S)-3-hydroxyadamantan-1-yl)glycine |
| VILD-023 | 1354835-82-7 | (S)-1-(N-formyl-N-((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carboxamide |
| VILD-024 | 1354835-84-9 | (1R,3r,5R,7S)-3-(N-(2-((S)-2-cyanopyrrolidin-1-yl)-2-oxoethyl)formamido)adamantan-1-yl 2,2,2-trifluoroacetate |
| VILD-025 | 1354835-83-8 | N-(2-((S)-2-cyanopyrrolidin-1-yl)-2-oxoethyl)-N-((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)formamide |
Frequently asked questions
What are the approved indications of Vildagliptin?
Approved indications include: 二型糖尿病.
When does the Vildagliptin patent expire?
No public expiry year is available for Vildagliptin yet; this page updates once verified.
How many synthesis routes are recorded for Vildagliptin?
6 synthesis routes are recorded; the shortest is 3 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Vildagliptin intermediates?
3 intermediate CAS of Vildagliptin are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Vildagliptin intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24