Unibest 优贝德
← Back to patent-cliff list

CAS 26407-07-8

4-(2-bromoethyl)aniline hydrochloride

Codes:MIRA-025a

Application context (from source-drug indications)

神经性膀胱功能障碍米拉贝隆膀胱过度活动症米拉贝隆

Source drugs (routes using this intermediate)

DrugTierExpiry
米拉贝隆MirabegronTier B — Position early2029

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

米拉贝隆优化路线steps: 4total yield: 60 g
(R)-2-amino-1-phenylethanol→2-(2-aminothiazol-4-yl)acetic acid hydrochloride→2-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)acetic acid→2-(2-(benzylamino)thiazol-4-yl)acetic acid→2-(2-((ethoxycarbonyl)amino)thiazol-4-yl)acetic acid→4-(2-bromoethyl)aniline hydrochloride→4-(2-chloroethyl)aniline hydrochloride→tert-butyl (4-(2-((4-(2-bromoethyl)phenyl)amino)-2-oxoethyl)thiazol-2-yl)carbamate→2-(2-(benzylamino)thiazol-4-yl)-N-(4-(2-bromoethyl)phenyl)acetamide→ethyl (4-(2-((4-(2-chloroethyl)phenyl)amino)-2-oxoethyl)thiazol-2-yl)carbamate→tert-butyl (4-(2-((4-(2-chloroethyl)phenyl)amino)-2-oxoethyl)thiazol-2-yl)carbamate→tert-butyl (R)-(4-(2-((4-(2-((2-hydroxy-2-phenylethyl)amino)ethyl)phenyl)amino)-2-oxoethyl)thiazol-2-yl)carbamate→(R)-2-(2-(benzylamino)thiazol-4-yl)-N-(4-(2-((2-hydroxy-2-phenylethyl)amino)ethyl)phenyl)acetamide→ethyl (R)-(4-(2-((4-(2-((2-hydroxy-2-phenylethyl)amino)ethyl)phenyl)amino)-2-oxoethyl)thiazol-2-yl)carbamate

Intermediates available on this site

No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.

This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.