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CAS 284462-37-9
4-(4-aminophenoxy)-N-methylpicolinamide
Codes：SORF-005
Application context (from source-drug indications)
甲状腺瘤甲苯磺酸索拉非尼肝细胞癌甲苯磺酸索拉非尼肾细胞癌甲苯磺酸索拉非尼侵袭性纤维瘤病甲苯磺酸索拉非尼肝癌甲苯磺酸索拉非尼骨髓增生性疾病甲苯磺酸索拉非尼
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 甲苯磺酸索拉非尼Sorafenib Tosylate | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
picolinic acid→4-chloropicolinoyl chloride hydrochloride→4-chloropicolinoyl chloride→4-aminophenol→4-(4-aminophenoxy)-N-methylpicolinamide→1-chloro-4-isocyanato-2-(trifluoromethyl)benzene→4-chloro-3-(trifluoromethyl)aniline
picolinic acid→4-chloropicolinoyl chloride→4-aminophenol→4-(4-aminophenoxy)-N-methylpicolinamide→phenyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate
4-(4-aminophenoxy)-N-methylpicolinamide→4-chloro-3-(trifluoromethyl)aniline
Intermediates available on this site
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