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CAS 5118-13-8

4-bromobenzo[b]thiophene

Codes:BREX-005

Application context (from source-drug indications)

精神分裂症布瑞哌唑阿尔茨海默病布瑞哌唑躁动布瑞哌唑抑郁布瑞哌唑抑郁症布瑞哌唑重度抑郁症布瑞哌唑

Source drugs (routes using this intermediate)

DrugTierExpiry
布瑞哌唑BrexpiprazoleTier A — Act now2029

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

布瑞哌唑原研路线steps: 3total yield: 13.6 g
7-hydroxyquinolin-2(1H)-one→1-bromo-4-chlorobutane→7-(4-chlorobutoxy)quinolin-2(1H)-one→1-(benzo[b]thiophen-4-yl)piperazine hydrochloride→4-bromobenzo[b]thiophene→piperazine

Intermediates available on this site

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SupplierProductPrice bandMOQLead timeQualifications
Unibest Taizhou GMP-like Site4-Bromobenzo[b]thiophene
Pharmaceutical Intermediates
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