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CAS 70500-72-0
7-hydroxyquinolin-2(1H)-one7-羟基喹啉-2(1H)-酮7-羟基-2-喹诺酮7-Hydroxycarbostyril
Codes：BREX-001
Physicochemical properties & identification
- Formula
- C9H7NO2
- Mol. weight
- 161.16
- Appearance
- 白色至类白色粉末
- Solubility
- 微溶于水，溶于热 DMF、DMSO 与碱液
- Storage
- 常温干燥避光
Applications
- · 布瑞哌唑（D2/5-HT1A 部分激动剂）喹啉酮母核关键中间体
- · 喹诺酮类杂环方法学研究的通用底物
Application context (from source-drug indications)
精神分裂症布瑞哌唑阿尔茨海默病布瑞哌唑躁动布瑞哌唑抑郁布瑞哌唑抑郁症布瑞哌唑重度抑郁症布瑞哌唑
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 布瑞哌唑Brexpiprazole | Tier A — Act now | 2029 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
7-hydroxyquinolin-2(1H)-one→1-bromo-4-chlorobutane→7-(4-chlorobutoxy)quinolin-2(1H)-one→1-(benzo[b]thiophen-4-yl)piperazine hydrochloride→4-bromobenzo[b]thiophene→piperazine
2-chloro-6-fluorobenzaldehyde→2-thioxothiazolidin-4-one→(Z)-5-(2,6-dichlorobenzylidene)-2-thioxothiazolidin-4-one→(Z)-3-(2,6-dichlorophenyl)-2-mercaptoacrylic acid→4-chlorobenzo[b]thiophene-2-carboxylic acid→4-chlorobenzo[b]thiophene→7-hydroxyquinolin-2(1H)-one→1-bromo-4-chlorobutane→7-(4-chlorobutoxy)quinolin-2(1H)-one→1-(benzo[b]thiophen-4-yl)piperazine hydrochloride
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications |
|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | 7-Hydroxyquinolinone Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.